Results 31 to 40 of about 5,601,044 (283)
Constrained cell penetrating peptides
Drug Discovery Today: Technologies, 2017 In this review we provide an overview of recent developments in the field of cell penetrating peptides (CPPs) on research that aims to achieve better control over their transduction properties - one of the big challenges - by means of restraining them.
S A, Bode, D W P M, Löwik
openaire +2 more sources
Novel approaches in development of cell penetrating peptides
Journal of Applied Pharmaceutical Research, 2021 Therapeutic cargos which are impermeable to the cell can be delivered by cell penetrating peptides (CPPs). CPP-cargo complexes accumulate by endocytosis inside the cells but they fail to reach the cytosolic space properly as they are often trapped in the
Vatsal R. Shah +2 more
doaj +1 more source
Functionalization of osmium arene anticancer complexes with (poly)arginine : effect on cellular uptake, internalization, and cytotoxicity [PDF]
, 2011 Attaching peptides to metallodrugs may result in improved biological properties of the complexes. The potential use of cell penetrating peptides (CPPs) as cell delivery vectors is attractive, since directed cell uptake of (metallo)drugs remains a major ...
Rijt, Sabine H. van +7 more
core +1 more source
Optimization of the cyclotide framework to improve cell penetration properties
Frontiers in Pharmacology, 2015 Cell penetrating peptides have been regarded as promising vectors to deliver hydrophilic molecules inside cells. Although they are great tools for research and have high potential as drug delivery systems, their application as drugs is impaired by their ...
Yen-Hua eHuang +4 more
doaj +1 more source
Communications Biology, 2023 Using a fluorescence complementation assay, Delivered Complementation in Planta (DCIP), we demonstrate cell-penetrating peptide-mediated cytosolic delivery of peptides and recombinant proteins in Nicotiana benthamiana.
Jeffrey W. Wang +7 more
doaj +1 more source
Antibacterial cell-penetrating peptides [PDF]
, 2021 The present disclosure relates to novel antibacterial cell penetrating peptides and derivatives, and methods to make and use the novel antibacterial cell-penetrating peptides and derivatives.
Chmielewski, Jean, Seleem, Mohamed N.
core
Effective Design of Multifunctional Peptides by Combining Compatible Functions.
PLoS Computational Biology, 2016 Multifunctionality is a common trait of many natural proteins and peptides, yet the rules to generate such multifunctionality remain unclear. We propose that the rules defining some protein/peptide functions are compatible. To explore this hypothesis, we
Christian Diener +6 more
doaj +1 more source
Classes and Prediction of Cell-Penetrating Peptides
, 2010 The classical view on how peptides enter cells has been changed due to the development in the research field of cell-penetrating peptides (CPPs). During the last 15 years, more than 100 peptide sequences have been published to enter cells and also to ...
Maria Lindgren +3 more
core +1 more source
Prospect of cell penetrating peptides in stem cell tracking
Stem Cell Research & Therapy, 2021 Stem cell therapy has shown great efficacy in many diseases. However, the treatment mechanism is still unclear, which is a big obstacle for promoting clinical research.
Xiaoshuang Zhang, Tong Lei, Hongwu Du
doaj +1 more source
Dendritic Guanidines as Efficient Analogues of Cell Penetrating Peptides
Pharmaceuticals, 2010 The widespread application of cell penetrating agents to clinical therapeutics and imaging agents relies on the ability to prepare them on a large scale and to readily conjugate them to their cargos. Dendritic analogues of cell penetrating peptides, with
Colin V. Bonduelle, Elizabeth R. Gillies
doaj +1 more source