Results 11 to 20 of about 31,021 (213)

Chemical-functional diversity in cell-penetrating peptides. [PDF]

open access: yesPLoS ONE, 2013
Cell-penetrating peptides (CPPs) are a promising tool to overcome cell membrane barriers. They have already been successfully applied as carriers for several problematic cargoes, like e.g.
Sofie Stalmans   +7 more
doaj   +1 more source

Editorial on Special Issue “Precision Delivery of Drugs and Imaging Agents with Peptides”

open access: yesPharmaceutics, 2022
Homing peptides and cell-penetrating peptides allow for systemic targeting of diseased tissues and/or efficient intracellular delivery of payloads [...]
Kaido Kurrikoff, Tambet Teesalu
doaj   +1 more source

Cell-penetrating peptides and their analogues as novel nanocarriers for drug delivery [PDF]

open access: yesBioImpacts, 2015
Introduction: The impermeability of biological membranes is a major obstacle in drug delivery; however, some peptides have transition capabilities of biomembranes.
Samira Jafari   +2 more
doaj   +1 more source

Redesigning of Cell-Penetrating Peptides to Improve Their Efficacy as a Drug Delivery System

open access: yesPharmaceutics, 2022
Cell-penetrating peptides (CPP) are promising tools for the transport of a broad range of compounds into cells. Since the discovery of the first members of this peptide family, many other peptides have been identified; nowadays, dozens of these peptides ...
Ildikó Szabó   +5 more
doaj   +1 more source

Cationic Cell-Penetrating Peptides Are Potent Furin Inhibitors. [PDF]

open access: yesPLoS ONE, 2015
Cationic cell-penetrating peptides have been widely used to enhance the intracellular delivery of various types of cargoes, such as drugs and proteins.
Bruno Ramos-Molina   +7 more
doaj   +1 more source

Nucleic acid delivery by cell-penetrating peptides [PDF]

open access: yesProceedings of the Estonian Academy of Sciences, 2023
Establishment of multiple novel mechanisms and applications of cell-penetrating peptides (CPP) has been demonstrated, leading to novel drug delivery systems.
Ülo Langel
doaj   +1 more source

Cell-penetrating peptides - Methods and protocols

open access: yesEuropean Journal of Histochemistry, 2011
Among the present day scientific frontiers, the researches on the cell-penetrating peptides has a special place since the scientific community has not yet reached a consensus even in the terminology on what we are referring to when we speak about cell ...
Carlo Alberto Redi
doaj   +1 more source

A manganese (II)-based coordinative dendrimer with robust efficiency in intracellular peptide delivery

open access: yesBioactive Materials, 2022
Peptides have gained increasing interests as drug candidates in modern pharmaceutical industry, however, the development of peptide drugs acting on intracellular targets is limited due to their membrane impermeability.
Lanfang Ren, Yang Gao, Yiyun Cheng
doaj   +1 more source

Potent antitumor effects of cell-penetrating peptides targeting STAT3 axis

open access: yesJCI Insight, 2021
To date, there are no inhibitors that directly and specifically target activated STAT3 and c-Myc in the clinic. Although peptide-based inhibitors can selectively block activated targets, their clinical usage is limited because of low cell penetration and/
Maryam Aftabizadeh   +11 more
doaj   +1 more source

Hybrid peptides inspired by the RWQWRWQWR sequence inhibit cervical cancer cells growth in vitro [PDF]

open access: yesExploration of Drug Science
Aim: The aim of this research was to generate new peptide molecules with cytotoxic activity against cervical cancer that can become effective in mitigating the impact of the disease and preventing its progression.
Natalia Ardila-Chantré   +7 more
doaj   +1 more source

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