Results 1 to 10 of about 993 (207)
Cell-Penetrating Peptides and Transportan [PDF]
Pharmaceutics, 2021 In the most recent 25–30 years, multiple novel mechanisms and applications of cell-penetrating peptides (CPP) have been demonstrated, leading to novel drug delivery systems.
Ulo Langel, Langel Ulo
exaly +5 more sources
Cell Penetrating Peptides in the Delivery of Biopharmaceuticals [PDF]
Biomolecules, 2012 The cell membrane is a highly selective barrier. This limits the cellular uptake of molecules including DNA, oligonucleotides, peptides and proteins used as therapeutic agents. Different approaches have been employed to increase the membrane permeability
Huixia Lv +2 more
exaly +5 more sources
Selective Moonlighting Cell-Penetrating Peptides [PDF]
Pharmaceutics, 2021 Cell penetrating peptides (CPPs) are molecules capable of passing through biological membranes. This capacity has been used to deliver impermeable molecules into cells, such as drugs and DNA probes, among others.
Rafael Morán-Torres +5 more
doaj +3 more sources
Applications of Cell-Penetrating Peptides for Tumor Targeting and Future Cancer Therapies
Pharmaceuticals, 2012 Cell-penetrating peptides provide a highly promising strategy for intracellular drug delivery. One relevant clinical application of cell-penetrating peptides is cancer therapeutics. Peptide based delivery could increase the uptake of drugs in tumor cells
Jakob Regberg +2 more
exaly +3 more sources
Frontiers in Microbiology, 2018 Designing drug delivery vehicles using cell-penetrating peptides is a hot area of research in the field of medicine. In the past, number of in silico methods have been developed for predicting cell-penetrating property of peptides containing natural ...
Piyush Agrawal +2 more
exaly +3 more sources
Internalization mechanisms of cell-penetrating peptides [PDF]
Beilstein Journal of Nanotechnology, 2020 In today’s modern era of medicine, macromolecular compounds such as proteins, peptides and nucleic acids are dethroning small molecules as leading therapeutics. Given their immense potential, they are highly sought after.
Ivana Ruseska, Andreas Zimmer
doaj +3 more sources
Cell-Penetrating Peptides—Mechanisms of Cellular Uptake and Generation of Delivery Systems
Pharmaceuticals, 2010 The successful clinical application of nucleic acid-based therapeutic strategies has been limited by the poor delivery efficiency achieved by existing vectors. The development of alternative delivery systems for improved biological activity is, therefore,
Sara Trabulo +2 more
exaly +3 more sources
Cell-Penetrating Milk-Derived Peptides with a Non-Inflammatory Profile
Molecules, 2023 Milk-derived peptides are known to confer anti-inflammatory effects. We hypothesised that milk-derived cell-penetrating peptides might modulate inflammation in useful ways.
Clement Agoni +8 more
doaj +1 more source
Designed Multifunctional Peptides for Intracellular Targets
Antibiotics, 2022 Nature’s way for bioactive peptides is to provide them with several related functions and the ability to cooperate in performing their job. Natural cell-penetrating peptides (CPP), such as penetratins, inspired the design of multifunctional constructs ...
Davor Juretić
doaj +1 more source
Prediction of cell penetrating peptides by support vector machines. [PDF]
PLoS Computational Biology, 2011 Cell penetrating peptides (CPPs) are those peptides that can transverse cell membranes to enter cells. Once inside the cell, different CPPs can localize to different cellular components and perform different roles.
William S Sanders +4 more
doaj +1 more source