Results 1 to 10 of about 61,707 (300)
Simple Model of the Transduction of Cell-Penetrating Peptides
, 2010 Cell-penetrating peptides (CPPs) such as HIV's trans-activating transcriptional activator (TAT) and polyarginine rapidly pass through the plasma membranes of mammalian cells by an unknown mechanism called transduction.
Andrews +40 more
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GENERATION OF MOUSE INDUCED PLURIPOTENT STEM CELLS BY PROTEIN TRANSDUCTION. [PDF]
, 2013 Somatic cell reprogramming has generated enormous interest after the first report by Yamanaka and his coworkers in 2006 on the generation of induced pluripotent stem cells (iPSCs) from mouse fibroblasts. Here we report the generation of stable iPSCs from
Andras Dinnyes +6 more
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The transcription factor ATF5: role in cellular differentiation, stress responses, and cancer. [PDF]
, 2017 Activating transcription factor 5 (ATF5) is a cellular prosurvival transcription factor within the basic leucine zipper (bZip) family that is involved in cellular differentiation and promotes cellular adaptation to stress.
Angelastro, James M, Sears, Thomas K
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Dendritic Guanidines as Efficient Analogues of Cell Penetrating Peptides
Pharmaceuticals, 2010 The widespread application of cell penetrating agents to clinical therapeutics and imaging agents relies on the ability to prepare them on a large scale and to readily conjugate them to their cargos. Dendritic analogues of cell penetrating peptides, with
Colin V. Bonduelle, Elizabeth R. Gillies
doaj +1 more source
Effect of small molecule signaling in PepFect14 transfection.
PLoS ONE, 2020 Cell-penetrating peptides can be used to deliver oligonucleotide-based cargoes into cells. Previous studies have shown that the use of small molecule drugs could be an efficient method to increase the efficacy of delivery of oligonucleotides by cell ...
Maxime Gestin +5 more
doaj +1 more source
COPA and SLC4A4 are required for cellular entry of arginine-rich peptides. [PDF]
PLoS ONE, 2014 Cell-penetrating peptides (CPPs) have gained attention as promising tools to enable the delivery of various molecules in a non-invasive manner. Among the CPPs, TAT and poly-arginine have been extensively utilized in numerous studies for the delivery of ...
Tomoyuki Tsumuraya, Masayuki Matsushita
doaj +1 more source
Addressing the needs of traumatic brain injury with clinical proteomics. [PDF]
, 2014 BackgroundNeurotrauma or injuries to the central nervous system (CNS) are a serious public health problem worldwide. Approximately 75% of all traumatic brain injuries (TBIs) are concussions or other mild TBI (mTBI) forms.
Loo, Joseph A +3 more
core +1 more source
Membranes, 2022 Cell-penetrating peptides rich in arginine are good candidates to be considered as antibacterial compounds, since peptides have a lower chance of generating resistance than commonly used antibiotics.
Mónica Aróstica +6 more
doaj +1 more source
Fluorescein Redirects a Ruthenium−Octaarginine Conjugate to the Nucleus [PDF]
, 2009 The cellular uptake and localization of a Ru−octaarginine conjugate with and without an appended fluorescein are compared. The inherent luminescence of the Ru(II) dipyridophenazine complex allows observation of its uptake without the addition of a ...
Barton, Jacqueline K., Puckett, Cindy A.
core +3 more sources
Properties of cell penetrating peptides (CPPs) [PDF]
IUBMB Life, 2006 Different approaches have been developed for the introduction of macromolecules, proteins and DNA into target cells. Viral (retroviruses, lentiviruses, etc.) and nonviral (liposomes, bioballistics etc.) vectors as well as lipid particles have been tested as DNA delivery systems.
Alexandre, Kerkis +3 more
openaire +2 more sources