Results 11 to 20 of about 993 (207)
Cell-Penetrating Peptide–Bismuth Bicycles
AbstractCell‐penetrating peptides (CPPs) play a significant role in the delivery of cargos into human cells. We report the first CPPs based on peptide‐bismuth bicycles, which can be readily obtained from commercially available peptide precursors, making them accessible for a wide range of applications.
Saan Voss +8 more
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Chemical-functional diversity in cell-penetrating peptides. [PDF]
Cell-penetrating peptides (CPPs) are a promising tool to overcome cell membrane barriers. They have already been successfully applied as carriers for several problematic cargoes, like e.g.
Sofie Stalmans +7 more
doaj +1 more source
Editorial on Special Issue “Precision Delivery of Drugs and Imaging Agents with Peptides”
Homing peptides and cell-penetrating peptides allow for systemic targeting of diseased tissues and/or efficient intracellular delivery of payloads [...]
Kaido Kurrikoff, Tambet Teesalu
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Glycosylated Cell‐Penetrating Peptides (GCPPs) [PDF]
AbstractThe cell membrane regulates the exchange of molecules and information with the external environment. However, this control barrier hinders the delivery of exogenous bioactive molecules that can be applied to correct cellular malfunctions. Therefore, the traffic of macromolecules across the cell membrane represents a great challenge for the ...
Iván Gallego +8 more
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Cell-penetrating peptides [PDF]
Internalization of cell-penetrating peptides, well described in mammalian cell system, has recently been reported in a range of plant cells by three independent groups. Despite fundamental differences between animal cell and plant cell composition, the CPP uptake pattern between the mammalian system and the plant system is very similar. Tat, Tat-2 pVEC
François, Eudes, Archana, Chugh
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Arginine‐rich cell‐penetrating peptides [PDF]
Arginine‐rich cell‐penetrating peptides are short cationic peptides capable of traversing the plasma membranes of eukaryotic cells. While successful intracellular delivery of many biologically active macromolecules has been accomplished using these peptides, their mechanisms of cell entry are still under investigation. Recent dialogue has centered on a
Schmidt, Nathan +3 more
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Uptake of cell‐penetrating peptides in yeasts [PDF]
The uptake of different cell‐penetrating peptides (CPPs) in two yeast species, Saccharomyces cerevisiae and Candida albicans, was studied using fluorescence HPLC‐analyses of cell content. Comparison of the ability of penetratin, pVEC and (KFF)3K to traverse the yeast cell envelope shows that the cellular uptake of the peptides varies widely.
Holm, Tina +4 more
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Cell-penetrating peptides and their analogues as novel nanocarriers for drug delivery [PDF]
Introduction: The impermeability of biological membranes is a major obstacle in drug delivery; however, some peptides have transition capabilities of biomembranes.
Samira Jafari +2 more
doaj +1 more source
Redesigning of Cell-Penetrating Peptides to Improve Their Efficacy as a Drug Delivery System
Cell-penetrating peptides (CPP) are promising tools for the transport of a broad range of compounds into cells. Since the discovery of the first members of this peptide family, many other peptides have been identified; nowadays, dozens of these peptides ...
Ildikó Szabó +5 more
doaj +1 more source
Cell-Penetrating Peptides [PDF]
Classes of Cell-Penetrating Peptides. Mechanisms of Cell Penetration, Interactions of Cell-Penetrating Peptides with Plasma Membranes and Lipid Models. Applications of Cell-Penetrating Peptides.
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