Results 11 to 20 of about 61,707 (300)
Selective Moonlighting Cell-Penetrating Peptides [PDF]
Pharmaceutics, 2021 Cell penetrating peptides (CPPs) are molecules capable of passing through biological membranes. This capacity has been used to deliver impermeable molecules into cells, such as drugs and DNA probes, among others.
Rafael Morán-Torres +5 more
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Cell-Penetrating Peptides and Transportan [PDF]
Pharmaceutics, 2021 In the most recent 25–30 years, multiple novel mechanisms and applications of cell-penetrating peptides (CPP) have been demonstrated, leading to novel drug delivery systems.
Ülo Langel
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Applications of Cell-Penetrating Peptides for Tumor Targeting and Future Cancer Therapies
Pharmaceuticals, 2012 Cell-penetrating peptides provide a highly promising strategy for intracellular drug delivery. One relevant clinical application of cell-penetrating peptides is cancer therapeutics. Peptide based delivery could increase the uptake of drugs in tumor cells
Ülo Langel +2 more
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Internalization mechanisms of cell-penetrating peptides [PDF]
Beilstein Journal of Nanotechnology, 2020 In today’s modern era of medicine, macromolecular compounds such as proteins, peptides and nucleic acids are dethroning small molecules as leading therapeutics. Given their immense potential, they are highly sought after.
Ivana Ruseska, Andreas Zimmer
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Bismuth-Cyclized Cell-Penetrating Peptides. [PDF]
Mol PharmIntracellular delivery of biological cargos, which would yield new research tools and novel therapeutics, remains an active area of research. A convenient and potentially general approach involves the conjugation of a cell-penetrating peptide to a cargo of interest. However, linear CPPs lack sufficient cytosolic entry efficiency and metabolic stability,
Ritchey JL, Filippi L, Ballard D, Pei D.
europepmc +3 more sources
Cell-penetrating peptides for sustainable agriculture. [PDF]
Trends Plant SciCell-penetrating peptides (CPPs) are short (typically 5-30 amino acids), cationic, amphipathic, or hydrophobic peptides that facilitate the cellular uptake of diverse cargo molecules by eukaryotic cells via direct translocation or endocytosis across the plasma membrane.
Patel P, Benzle K, Pei D, Wang GL.
europepmc +4 more sources
Beyond Transduction: Anti-Inflammatory Effects of Cell Penetrating Peptides [PDF]
MoleculesOne of the bottlenecks to bringing new therapies to the clinic has been a lack of vectors for delivering novel therapeutics in a targeted manner. Cell penetrating peptides (CPPs) have received a lot of attention and have been the subject of numerous ...
Jack Lopuszynski +2 more
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Cell Penetrating Peptides [PDF]
, 2022 Classes of Cell-Penetrating Peptides. Mechanisms of Cell Penetration, Interactions of Cell-Penetrating Peptides with Plasma Membranes and Lipid Models. Applications of Cell-Penetrating Peptides.
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Cell-Penetrating Milk-Derived Peptides with a Non-Inflammatory Profile
Molecules, 2023 Milk-derived peptides are known to confer anti-inflammatory effects. We hypothesised that milk-derived cell-penetrating peptides might modulate inflammation in useful ways.
Clement Agoni +8 more
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Designed Multifunctional Peptides for Intracellular Targets
Antibiotics, 2022 Nature’s way for bioactive peptides is to provide them with several related functions and the ability to cooperate in performing their job. Natural cell-penetrating peptides (CPP), such as penetratins, inspired the design of multifunctional constructs ...
Davor Juretić
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