Results 11 to 20 of about 5,562,033 (283)
Cell-Penetrating Peptides [PDF]
, 2011 Classes of Cell-Penetrating Peptides. Mechanisms of Cell Penetration, Interactions of Cell-Penetrating Peptides with Plasma Membranes and Lipid Models. Applications of Cell-Penetrating Peptides.
Kristensen, Mie +8 more
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, 2021 In this introductory chapter, we first define cell-penetrating peptides (CPPs), give short overview of CPP history and discuss several aspects of CPP classification. Next section is devoted to the mechanism of CPP penetration into the cells, where direct and endocytic internalization of CPP is explained.
Matjaž, Zorko, Ülo, Langel
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Prediction of Cell-Penetrating Peptides
, 2015 The in silico methods for the prediction of the cell-penetrating peptides are reviewed. Those include the multivariate statistical methods, machine-learning methods such as the artificial neural networks and support vector machines, and molecular modeling techniques including molecular docking and molecular dynamics.The applicability of the methods is ...
Mattias, Hällbrink, Mati, Karelson
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Classes of Cell-Penetrating Peptides
, 2015 During the three decades of cell-penetrating peptides era the superfamily of CPPs has rapidly expanded, and the quest for new sequences continues. CPPs have been well recognized by scientific community and they have been used for transduction of a wide variety of molecules and particles into cultured cells and in vivo.
Margus, Pooga, Ülo, Langel
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Cell-penetrating peptides - Methods and protocols
European Journal of Histochemistry, 2011 Among the present day scientific frontiers, the researches on the cell-penetrating peptides has a special place since the scientific community has not yet reached a consensus even in the terminology on what we are referring to when we speak about cell ...
Carlo Alberto Redi
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Cell Penetrating Peptides, Novel Vectors for Gene Therapy
Pharmaceutics, 2020 Cell penetrating peptides (CPPs), also known as protein transduction domains (PTDs), first identified ~25 years ago, are small, 6−30 amino acid long, synthetic, or naturally occurring peptides, able to carry variety of cargoes across the cellular ...
Rebecca E. Taylor, Maliha Zahid
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Cell Penetrating Peptides in the Delivery of Biopharmaceuticals
Biomolecules, 2012 The cell membrane is a highly selective barrier. This limits the cellular uptake of molecules including DNA, oligonucleotides, peptides and proteins used as therapeutic agents. Different approaches have been employed to increase the membrane permeability
Jianping Zhou +4 more
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Cell-penetrating peptides and their analogues as novel nanocarriers for drug delivery [PDF]
BioImpacts, 2015 Introduction: The impermeability of biological membranes is a major obstacle in drug delivery; however, some peptides have transition capabilities of biomembranes.
Samira Jafari +2 more
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Redesigning of Cell-Penetrating Peptides to Improve Their Efficacy as a Drug Delivery System
Pharmaceutics, 2022 Cell-penetrating peptides (CPP) are promising tools for the transport of a broad range of compounds into cells. Since the discovery of the first members of this peptide family, many other peptides have been identified; nowadays, dozens of these peptides ...
Ildikó Szabó +5 more
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Cell-Penetrating Peptide–Bismuth Bicycles
Angewandte Chemie, 2023 Cell-penetrating peptides (CPPs) play a significant role in the delivery of cargos into human cells for a wide range of therapeutic and diagnostic applications. We disclose the first CPPs based on peptide–bismuth bicycles, which can be readily obtained from commercially available peptide precursors, making them highly accessible for a wide range of ...
Saan Voss +8 more
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