Results 21 to 30 of about 61,707 (300)
Cell-Penetrating Peptide–Bismuth Bicycles
Angewandte Chemie, 2023 Cell-penetrating peptides (CPPs) play a significant role in the delivery of cargos into human cells for a wide range of therapeutic and diagnostic applications. We disclose the first CPPs based on peptide–bismuth bicycles, which can be readily obtained from commercially available peptide precursors, making them highly accessible for a wide range of ...
Saan Voss +8 more
openaire +2 more sources
Prediction of cell penetrating peptides by support vector machines. [PDF]
PLoS Computational Biology, 2011 Cell penetrating peptides (CPPs) are those peptides that can transverse cell membranes to enter cells. Once inside the cell, different CPPs can localize to different cellular components and perform different roles.
William S Sanders +4 more
doaj +1 more source
Glycosylated Cell‐Penetrating Peptides (GCPPs) [PDF]
ChemBioChem, 2019 AbstractThe cell membrane regulates the exchange of molecules and information with the external environment. However, this control barrier hinders the delivery of exogenous bioactive molecules that can be applied to correct cellular malfunctions. Therefore, the traffic of macromolecules across the cell membrane represents a great challenge for the ...
Iván Gallego +8 more
openaire +4 more sources
Matrix stiffness affects endocytic uptake of MK2-inhibitor peptides. [PDF]
, 2013 In this study, the role of substrate stiffness on the endocytic uptake of a cell-penetrating peptide was investigated. The cell-penetrating peptide, an inhibitor of mitogen-activated protein kinase activated protein kinase II (MK2), enters a primary ...
Brugnano, Jamie L, Panitch, Alyssa
core +10 more sources
Chemical-functional diversity in cell-penetrating peptides. [PDF]
PLoS ONE, 2013 Cell-penetrating peptides (CPPs) are a promising tool to overcome cell membrane barriers. They have already been successfully applied as carriers for several problematic cargoes, like e.g.
Sofie Stalmans +7 more
doaj +1 more source
Editorial on Special Issue “Precision Delivery of Drugs and Imaging Agents with Peptides”
Pharmaceutics, 2022 Homing peptides and cell-penetrating peptides allow for systemic targeting of diseased tissues and/or efficient intracellular delivery of payloads [...]
Kaido Kurrikoff, Tambet Teesalu
doaj +1 more source
Arginine‐rich cell‐penetrating peptides [PDF]
FEBS Letters, 2009 Arginine‐rich cell‐penetrating peptides are short cationic peptides capable of traversing the plasma membranes of eukaryotic cells. While successful intracellular delivery of many biologically active macromolecules has been accomplished using these peptides, their mechanisms of cell entry are still under investigation. Recent dialogue has centered on a
Schmidt, Nathan +3 more
openaire +2 more sources
Frontiers in Microbiology, 2018 Designing drug delivery vehicles using cell-penetrating peptides is a hot area of research in the field of medicine. In the past, number of in silico methods have been developed for predicting cell-penetrating property of peptides containing natural ...
Vinod Kumar +11 more
doaj +1 more source
Cell-penetrating peptides and their analogues as novel nanocarriers for drug delivery [PDF]
BioImpacts, 2015 Introduction: The impermeability of biological membranes is a major obstacle in drug delivery; however, some peptides have transition capabilities of biomembranes.
Samira Jafari +2 more
doaj +1 more source
Synthesis and cellular penetration properties of new phosphonium based cationic amphiphilic peptides [PDF]
, 2018 A new category of phosphonium based cationic amphiphilic peptides has been developed and evaluated as potential antimicrobial peptides and cell penetrating peptides.
Gannon, Susan +7 more
core +1 more source