Results 41 to 50 of about 5,562,033 (283)
Optimization of the cyclotide framework to improve cell penetration properties
Frontiers in Pharmacology, 2015 Cell penetrating peptides have been regarded as promising vectors to deliver hydrophilic molecules inside cells. Although they are great tools for research and have high potential as drug delivery systems, their application as drugs is impaired by their ...
Yen-Hua eHuang +4 more
doaj +1 more source
Prospect of cell penetrating peptides in stem cell tracking
Stem Cell Research & Therapy, 2021 Stem cell therapy has shown great efficacy in many diseases. However, the treatment mechanism is still unclear, which is a big obstacle for promoting clinical research.
Xiaoshuang Zhang, Tong Lei, Hongwu Du
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Classes and Prediction of Cell-Penetrating Peptides
, 2010 The classical view on how peptides enter cells has been changed due to the development in the research field of cell-penetrating peptides (CPPs). During the last 15 years, more than 100 peptide sequences have been published to enter cells and also to ...
Maria Lindgren +3 more
core +1 more source
Dendritic Guanidines as Efficient Analogues of Cell Penetrating Peptides
Pharmaceuticals, 2010 The widespread application of cell penetrating agents to clinical therapeutics and imaging agents relies on the ability to prepare them on a large scale and to readily conjugate them to their cargos. Dendritic analogues of cell penetrating peptides, with
Colin V. Bonduelle, Elizabeth R. Gillies
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Cell penetrating peptides as signal transduction modulators
, 2006 THIS BOOK: Since the first Handbook of Cell-Penetrating Peptides was prepared in 2001, the wealth of new information on the use of these peptides as transport systems has in fact served to confound the field.
Jones, Sarah, Howl, John D.
core +1 more source
Effect of small molecule signaling in PepFect14 transfection.
PLoS ONE, 2020 Cell-penetrating peptides can be used to deliver oligonucleotide-based cargoes into cells. Previous studies have shown that the use of small molecule drugs could be an efficient method to increase the efficacy of delivery of oligonucleotides by cell ...
Maxime Gestin +5 more
doaj +1 more source
The Antimicrobial and Antiviral Applications of Cell-Penetrating Peptides
, 2015 Over the past two decades, cell-penetrating peptides (CPPs) have become increasingly popular both in research and in application. There have been numerous studies on the physiochemical characteristics and behavior of CPPs in various environments ...
Eriste, Elo +5 more
core +1 more source
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
COPA and SLC4A4 are required for cellular entry of arginine-rich peptides. [PDF]
PLoS ONE, 2014 Cell-penetrating peptides (CPPs) have gained attention as promising tools to enable the delivery of various molecules in a non-invasive manner. Among the CPPs, TAT and poly-arginine have been extensively utilized in numerous studies for the delivery of ...
Tomoyuki Tsumuraya, Masayuki Matsushita
doaj +1 more source