Results 31 to 40 of about 5,562,033 (283)
Beyond the discovered peptides by Viktor Mutt – a contribution [PDF]
Proceedings of the Estonian Academy of SciencesA summary of the results obtained in the collaboration between the laboratory of Prof. Viktor Mutt at Karolinska Institutet and our laboratory at Stockholm University, headed by Prof. Tamas Bartfai, is given.
Ülo Langel
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Uptake of cell‐penetrating peptides in yeasts [PDF]
FEBS Letters, 2005 The uptake of different cell‐penetrating peptides (CPPs) in two yeast species, Saccharomyces cerevisiae and Candida albicans, was studied using fluorescence HPLC‐analyses of cell content. Comparison of the ability of penetratin, pVEC and (KFF)3K to traverse the yeast cell envelope shows that the cellular uptake of the peptides varies widely.
Holm, Tina +4 more
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Internalization mechanisms of cell-penetrating peptides
Beilstein Journal of Nanotechnology, 2020 In today’s modern era of medicine, macromolecular compounds such as proteins, peptides and nucleic acids are dethroning small molecules as leading therapeutics. Given their immense potential, they are highly sought after.
Ivana Ruseska, Andreas Zimmer
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Ligands for oral delivery of peptides across the blood-brain-barrier
Acta Materia Medica, 2022 Peptides are short chains of amino acids linked by peptide bonds. Many peptides and proteins are limited by their poor enzymatic stability and permeability across the intestinal epithelial membranes and/or blood-brain barrier (BBB).
Murad Al Gailani +2 more
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Constrained cell penetrating peptides
Drug Discovery Today: Technologies, 2017 In this review we provide an overview of recent developments in the field of cell penetrating peptides (CPPs) on research that aims to achieve better control over their transduction properties - one of the big challenges - by means of restraining them.
S A, Bode, D W P M, Löwik
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Novel approaches in development of cell penetrating peptides
Journal of Applied Pharmaceutical Research, 2021 Therapeutic cargos which are impermeable to the cell can be delivered by cell penetrating peptides (CPPs). CPP-cargo complexes accumulate by endocytosis inside the cells but they fail to reach the cytosolic space properly as they are often trapped in the
Vatsal R. Shah +2 more
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Functionalization of osmium arene anticancer complexes with (poly)arginine : effect on cellular uptake, internalization, and cytotoxicity [PDF]
, 2011 Attaching peptides to metallodrugs may result in improved biological properties of the complexes. The potential use of cell penetrating peptides (CPPs) as cell delivery vectors is attractive, since directed cell uptake of (metallo)drugs remains a major ...
Rijt, Sabine H. van +7 more
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Communications Biology, 2023 Using a fluorescence complementation assay, Delivered Complementation in Planta (DCIP), we demonstrate cell-penetrating peptide-mediated cytosolic delivery of peptides and recombinant proteins in Nicotiana benthamiana.
Jeffrey W. Wang +7 more
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Antibacterial cell-penetrating peptides [PDF]
, 2021 The present disclosure relates to novel antibacterial cell penetrating peptides and derivatives, and methods to make and use the novel antibacterial cell-penetrating peptides and derivatives.
Chmielewski, Jean, Seleem, Mohamed N.
core
Effective Design of Multifunctional Peptides by Combining Compatible Functions.
PLoS Computational Biology, 2016 Multifunctionality is a common trait of many natural proteins and peptides, yet the rules to generate such multifunctionality remain unclear. We propose that the rules defining some protein/peptide functions are compatible. To explore this hypothesis, we
Christian Diener +6 more
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