Results 31 to 40 of about 61,707 (300)

Redesigning of Cell-Penetrating Peptides to Improve Their Efficacy as a Drug Delivery System

open access: yesPharmaceutics, 2022
Cell-penetrating peptides (CPP) are promising tools for the transport of a broad range of compounds into cells. Since the discovery of the first members of this peptide family, many other peptides have been identified; nowadays, dozens of these peptides ...
Ildikó Szabó   +5 more
doaj   +1 more source

Nucleic acid delivery by cell-penetrating peptides [PDF]

open access: yesProceedings of the Estonian Academy of Sciences, 2023
Establishment of multiple novel mechanisms and applications of cell-penetrating peptides (CPP) has been demonstrated, leading to novel drug delivery systems.
Ülo Langel
doaj   +1 more source

Cell-penetrating Peptides [PDF]

open access: yesJournal of Biological Chemistry, 2003
The present invention discloses cell penetrating peptides and conjugates of a cell penetrating peptide and a cargo molecule.
Jean Philippe Richard   +7 more
openaire   +1 more source

Cell-penetrating peptides [PDF]

open access: yesPlant Signaling & Behavior, 2008
Internalization of cell-penetrating peptides, well described in mammalian cell system, has recently been reported in a range of plant cells by three independent groups. Despite fundamental differences between animal cell and plant cell composition, the CPP uptake pattern between the mammalian system and the plant system is very similar. Tat, Tat-2 pVEC
François, Eudes, Archana, Chugh
openaire   +2 more sources

Cationic Cell-Penetrating Peptides Are Potent Furin Inhibitors. [PDF]

open access: yesPLoS ONE, 2015
Cationic cell-penetrating peptides have been widely used to enhance the intracellular delivery of various types of cargoes, such as drugs and proteins.
Bruno Ramos-Molina   +7 more
doaj   +1 more source

Constrained cell penetrating peptides

open access: yesDrug Discovery Today: Technologies, 2017
In this review we provide an overview of recent developments in the field of cell penetrating peptides (CPPs) on research that aims to achieve better control over their transduction properties - one of the big challenges - by means of restraining them.
S A, Bode, D W P M, Löwik
openaire   +2 more sources

Cell-penetrating peptides - Methods and protocols

open access: yesEuropean Journal of Histochemistry, 2011
Among the present day scientific frontiers, the researches on the cell-penetrating peptides has a special place since the scientific community has not yet reached a consensus even in the terminology on what we are referring to when we speak about cell ...
Carlo Alberto Redi
doaj   +1 more source

The vimentin-tubulin binding site peptide (Vim-TBS.58-81) crosses the plasma membrane and enters the nuclei of human glioma cells [PDF]

open access: yes, 2012
Cell-penetrating peptides (CPPs) can translocate through the plasma membrane and localize in different cell compartments providing a promising delivery system for peptides, proteins, nucleic acids, and other products. Here we describe features of a novel
A. Peterson, J. Balzeau, J. Eyer
core   +3 more sources

Potent antitumor effects of cell-penetrating peptides targeting STAT3 axis

open access: yesJCI Insight, 2021
To date, there are no inhibitors that directly and specifically target activated STAT3 and c-Myc in the clinic. Although peptide-based inhibitors can selectively block activated targets, their clinical usage is limited because of low cell penetration and/
Maryam Aftabizadeh   +11 more
doaj   +1 more source

A manganese (II)-based coordinative dendrimer with robust efficiency in intracellular peptide delivery

open access: yesBioactive Materials, 2022
Peptides have gained increasing interests as drug candidates in modern pharmaceutical industry, however, the development of peptide drugs acting on intracellular targets is limited due to their membrane impermeability.
Lanfang Ren, Yang Gao, Yiyun Cheng
doaj   +1 more source

Home - About - Disclaimer - Privacy