Results 151 to 160 of about 235,556 (291)

Epigenetic Regulation of Immune Dysfunction in Chronic Prostatitis/Chronic Pelvic Pain Syndrome

The Prostate, EarlyView.
ABSTRACT Background Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) is a prevalent and debilitating condition with unclear etiology. Increasing evidence implicates immune dysregulation, yet the molecular mechanisms underlying impaired immune regulation remain poorly defined. This study investigated the role of altered immune responses within
Praveen Thumbikat, Goutham Pattabiraman, Farzaneh Sharifzad, Yongyong Yang, Zhiqiang Liu, Catherine V. Osborn, Stephen F. Murphy, Qi Cao, Anthony J. Schaeffer   +8 more
wiley   +1 more source

Cognitive Outcome After Deep Brain Stimulation for Refractory Obsessive–Compulsive Disorder: A Systematic Review

Neuromodulation: Technology at the Neural Interface, EarlyView., 2021
Abstract Introduction Deep brain stimulation (DBS) is an effective treatment for refractory obsessive–compulsive disorder (OCD). Neuropsychological assessment contributes to DBS treatment in several ways: it monitors the cognitive safety of the treatment, identifies beneficial or detrimental cognitive side effects and it could aid to explain ...
Tim A. M. Bouwens van der Vlis, Annelien Duits, Mégan M. G. H. van de Veerdonk, Anne E. P. Mulders, Koen R. J. Schruers, Yasin Temel, Linda Ackermans, Albert F. G. Leentjens   +7 more
wiley   +1 more source

Screening of Phytotoxins in Raw Honey and the Honey Sugar Matrix's Modulatory Effects on Their Toxicity. [PDF]

Foods
Yang L, Xiao T, Yang X, Yang L, Shen W, Huang Z, Nie G, Dong C, Jin X, Tang Q, Lu Y, Zheng Y.   +11 more
europepmc   +1 more source

Intranasal diamorphine population pharmacokinetics modeling and simulation in pediatric breakthrough pain

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 435-447, March 2025.
Abstract Intranasal diamorphine (IND), approved for managing breakthrough pain in the UK, has been identified as an acceptable alternative offering effective, expedient, and less traumatic analgesia for children. However, the current dose regimen in pediatric populations relies on clinical expertise while the pharmacokinetics properties are poorly ...
Lianjin Cai, Jingchen Zhai, Beihong Ji, Fengyang Han, Taoyu Niu, Luxuan Wang, Junmei Wang   +6 more
wiley   +1 more source

Similarities and differences in carotid artery, hemodynamic, and autonomic reactivity induced by mental stress or cold in adults: A randomized crossover study. [PDF]

Physiol Rep
Fensterseifer FJ, Teixeira IG, Oracz W, Filipini RE, Stein F, Speretta GF.   +5 more
europepmc   +1 more source

Advancing pharmacometrics in Africa—Transition from capacity development toward job creation

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 407-419, March 2025.
Abstract Trained pharmacometricians remain scarce in Africa due to limited training opportunities, lack of a pharmaceutical product development ecosystem, and emigration to high‐income countries. The Applied Pharmacometrics Training (APT) fellowship program was established to address these gaps and specifically foster job creation for talent retention.
Goonaseelan (Colin) Pillai, Samer Mouksassi, Innocent G. Asiimwe, Craig R. Rayner, Steven Kern, Phumla Sinxadi, Paolo Denti, Eric Decloedt, Catriona Waitt, Bernhards R. Ogutu, Rik de Greef   +10 more
wiley   +1 more source

Periodontitis and atherosclerotic cardiovascular disease: A critical appraisal

Periodontology 2000, EarlyView., 2023
Abstract In spite of intensive research efforts driving spectacular advances in terms of prevention and treatments, cardiovascular diseases (CVDs) remain a leading health burden, accounting for 32% of all deaths (World Health Organization. “Cardiovascular Diseases (CVDs).” WHO, February 1, 2017, https://www.who.int/news‐room/fact‐sheets/detail ...
Maria Clotilde Carra, Hélène Rangé, Giuseppina Caligiuri, Philippe Bouchard   +3 more
wiley   +1 more source

Enhancing Tea Agrifood System Resilience Amid Geopolitical Tensions: A Resource Nexus‐Based System Dynamics Analysis

Sustainable Development, EarlyView.
ABSTRACT Geopolitical conflicts are increasingly threatening global food security, economic stability, and peace, impacting Tanzania's tea agrifood system. This study develops a quantitative Resource Nexus‐based system dynamics simulation model assessing the feedbacks and interdependencies among key environmental and socioeconomic resources shaping ...
Ally Mkumbukiy, Daniel Mgori, Edeltraud Guenther, Kaveh Madani   +3 more
wiley   +1 more source

Titanium Dioxide Induced Immobilization of Small Platinum Nanoparticles on Carbon Spherogels: A Strategy Towards Stable and Efficient Electrocatalysts for the Hydrogen Evolution Reaction

Small, EarlyView.
Platinum nanoparticles are immobilized on hollow carbon spherogels using supercritical deposition, enabling precise control over nanoparticle size, loading, and spatial distribution. Incorporation of an internal TiO2 sublayer in the hollow sphere support induces enhanced metal–support interactions, markedly improving hydrogen evolution activity and ...
Philip S. Pein, Ala Alsuhile, Simon Penner, Asghar Mohammadi, Gregor A. Zickler, Aseel Almohammad, Finn Baron, Mathis Kirstein, Can Erkey, Irina Smirnova, Michael S. Elsaesser, Baldur Schroeter   +11 more
wiley   +1 more source

Do machine learning models add value in assessing operative stress? [PDF]

Surgery
Jacobs MA, Shireman PK, Silverstein JC, Hall DE.   +3 more
europepmc   +1 more source