Results 171 to 180 of about 77,049 (267)

PARP1 trapping activates ATM-mediated NF-κB signaling independent of replication in response to TOP1 blockade. [PDF]

Nucleic Acids Res
Bournique E, Sanchez A, Ha K, Yan KM, Manjunath L, Santiago G, Ortega P, Buisson R.   +7 more
europepmc   +1 more source

The metalloproteinase ADAM17 promotes acute lung inflammatory responses during pancreatitis

British Journal of Pharmacology, EarlyView.
Background and Purpose Acute pancreatitis (AP) is a multifactorial upper gastrointestinal inflammatory disorder that in severe cases (~20% of all AP) is associated with substantial morbidity and mortality, the latter coincident with multiorgan dysfunction, particularly acute lung injury (ALI).
Shermin Chan, Karen Hon, Ruby E. Dawson, Teresa Weng, Jelena Solujic, Yu C. J. Chey, James D. Zuiani, Griffith B. Perkins, P. Toby Coates, Chris Drogemuller, Eddie Sanderlin, Lulu Huang, John Finnie, Stefan Rose‐John, Arash Badiei, Phan Nguyen, Brendan J. Jenkins, Mohamed I. Saad   +17 more
wiley   +1 more source

Validation and Development of Claims-Based Algorithms for Identifying Thyroid Eye Disease Using the IRIS Registry-Komodo Linked Database. [PDF]

J Clin Med
Ma J, Lee WW, Brookhart MA, Tamhankar MA, Ayala-Haedo J, He F, Patel H.   +6 more
europepmc   +1 more source

Polarized effects of adenosine on blood–brain barrier integrity: Tightening from the luminal and opening from the abluminal side

British Journal of Pharmacology, EarlyView.
Background and Purpose Adenosine as a signalling molecule modifies blood–brain barrier (BBB) tightness in pathological conditions. Our aim was to investigate the direct and polarized effects of adenosine on the BBB using co‐culture and in vivo models. Experimental Approach The expression of adenosine receptors was measured by qRT‐PCR.
András Harazin, Gabriela Hurtado‐Alvarado, Lilla Barna, Arturo Contis‐Montes de Oca, Rocío Ruíz‐Manzano, Krisztián Laczi, András Kincses, Gergő Porkoláb, Gang Chen, Beatriz Gómez‐González, Mária A. Deli   +10 more
wiley   +1 more source

Evaluating the Effect of Packaging Materials on Extra Virgin Olive Oil Quality Under Simulated Household Use and Storage Conditions. [PDF]

Foods
Sordini B, Urbani S, Selvaggini R, Taticchi A, Servili M, Dottori I, Veneziani G, Famiani F, Bonucci A, Nucciarelli D, Esposto S.   +10 more
europepmc   +1 more source

A Nationwide Central Diagnosis for Pediatric CNS Tumors in Japan: The JCCG Brain Tumor and Pathology Committees

Cancer Science, EarlyView.
In this report, we present the results of a nationwide initiative launched by the Japan Children's Cancer Group to provide integrated diagnoses for pediatric central nervous system (CNS) tumors, incorporating central pathological review and molecular profiling.
Yoshiko Nakano, Junko Hirato, Takako Yoshioka, Tetsuya Takimoto, Sumihito Nobusawa, Kaishi Satomi, Ran Tomomasa, Seiji Yamada, Taku Homma, Shoh Sasaki, Ayako Yamazaki, Maki Sakaguchi, Yasuhide Takeuchi, Nei Fukazawa, Kai Yamasaki, Kohei Fukuoka, Yui Shinohara Kimura, Yuki Nagayama, Yohei Inoue, Akira Miyahira, Ema Yoshioka, Asako Katsuma, Hayato Fukusumi, Tomoko Shofuda, Yuko Hibiya, Yuko Matsushita, Mai Honda Kitahara, Yuki Yomoda, Miho Kato, Michael D. Taylor, Yasuhito Arai, Tatsuhiro Shibata, Hiroaki Sakamoto, Keita Terashima, Yoshiki Arakawa, Toshihiro Kumabe, Ryo Nishikawa, Junichi Hara, Yonehiro Kanemura, Koichi Ichimura   +39 more
wiley   +1 more source

Synergistic Anticancer Effects of Resveratrol and Carboplatin in Y79 Retinoblastoma Cells: Mechanistic Insights into Apoptosis, G2/M Arrest, and ROS-Dependent Mitochondrial Dysfunction. [PDF]

Int J Mol Sci
Maçin A, Duman E, Özdemir İ, Tuncer MC.   +3 more
europepmc   +1 more source

Implementing a behavioural intervention for paediatric type 1 diabetes: Key informant perspectives of multilevel barriers and facilitators

Diabetic Medicine, EarlyView.
Providers, healthcare leaders, adolescents and caregivers identified evidence of intervention effectiveness in lowering glycaemic levels as a key facilitator of implementing a type 1 diabetes behavioural intervention. Critical barriers to implementation include buy‐in among clinic leaders, resource availability within clinics and meeting families ...
Julia Price, Janet A. Deatrick, Geoffrey Curran, Chia‐Lun Yang, Alejandra Perez Ramirez, Courtney Thomas, Anne E. Kazak   +6 more
wiley   +1 more source

Arginine methylation of human DNA topoisomerase I by PRMT5 facilitates DNA relaxation. [PDF]

Nucleic Acids Res
Basu S, Bhattacharyya A, Khan MA, Pal U, Chowdhuri SP, Satrusal SR, Baranello L, Datta D, Das BB.   +8 more
europepmc   +1 more source