Results 191 to 200 of about 118,210 (303)

Smart mesoporous silica nanoparticles for precision cancer therapy: Tumor targeting and stimuli‐responsive controlled release

open access: yesSmart Molecules, EarlyView.
Smart mesoporous silica nanoparticles integrate tunable pore structures, molecular gates, targeting ligands, and stimuli‐responsive components to achieve controlled drug release for precision cancer therapy. This review highlights design principles, therapeutic applications, and future directions in immunotherapy, biodegradability, biosafety, and ...
Majdi Al‐Amili, Lei Lei, Zhu Jin
wiley   +1 more source

Under‐documentation of social determinants of health in kidney stone patients in high‐risk region

open access: yesUroPrecision, EarlyView.
Abstract Background Social determinants or drivers of health (SDoH) provide a broad perspective of influences on patient health. An association between poorer SDoH and worse outcomes for kidney stone disease exists. Many electronic health records (EHR) contain an intake feature to record SDoH data; however, no data exist on the use of this feature ...
Jennifer R. Mihalo   +9 more
wiley   +1 more source

Physiological Emergency Surgery Acuity Score Predicts Mortality and Anastomotic Leak in Emergency Laparotomy: An External Validation Study

open access: yesWorld Journal of Surgery, EarlyView.
PESAS demonstrates good discrimination, calibration‐in‐the‐large, and net benefit as an ordinal risk stratification tool for prediction of 30‐day mortality among patients undergoing emergency laparotomy, with exploratory analysis suggesting promise for predicting anastomotic leak.
Wade Hopper   +2 more
wiley   +1 more source

Assessment of Major Adverse Cardiovascular Event Across Diverse Racial Groups of Psoriasis Patients on Biologic Therapy: A Retrospective Cohort Study

open access: yesThe Journal of Dermatology, EarlyView.
ABSTRACT Psoriasis is associated with an increased risk of major adverse cardiovascular events (MACE), and biologic therapy may reduce this risk by targeting systemic inflammation. However, limited data exist on whether long term MACE risk differs by biologic class or across racial groups. We conducted a retrospective cohort study to assess the risk of
Chunghwan Ro   +3 more
wiley   +1 more source

Expanding the Use of PAVA Spray in Young Offender Institutions: The King (on the application of The Howard League for Penal Reform) v The Secretary of State for Justice

open access: yesThe Modern Law Review, EarlyView.
This case note critically examines the January 2026 High Court judgment in The King (on the application of The Howard League for Penal Reform) v The Secretary of State for Justice which dismissed a judicial review challenging the expansion of the use of PAVA spray in Young Offender Institutions (YOIs) in England.
Raymond Arthur
wiley   +1 more source

How common is alcohol use disorder in posttraumatic stress disorder? A systematic review, meta‐analysis, and moderator analysis

open access: yesThe American Journal on Addictions, EarlyView.
Abstract Background and Objectives Comorbidity between posttraumatic stress disorder (PTSD) and alcohol use disorder (AUD) complicates care, yet reported prevalence varies widely across settings and methods. We estimated AUD prevalence among adults with PTSD and identified sources of variability.
Maria Olivia Pozzolo Pedro   +6 more
wiley   +1 more source

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