Total <i>Sanghuangporus vaninii</i> Extract Ameliorates Cisplatin-Induced Glioma Cell Death by Regulating Ferroptosis and Inflammation. [PDF]
Xu Y +5 more
europepmc +1 more source
KU80 suppresses endonuclease G activity to preserve genomic integrity
Under normal conditions, EndoG remains restricted to mitochondria and the genome remains intact. When KU80 is absent, EndoG translocates into the nucleus, where it promotes DNA fragmentation and genomic instability. Thus, this work highlights the importance of KU80 in tightly controlling EndoG localization to preserve genome stability.
Jargalan Batsaikhan +8 more
wiley +1 more source
Trends in Medicare Office-Based Procedures for Chronic Rhinitis and Nasal Obstruction. [PDF]
Jeong SS, Arnold M.
europepmc +1 more source
From hepatic to hematopoietic: LRH‐1's expanding cellular repertoire to the immune system
The nuclear receptor LRH‐1 is a well‐characterized regulator of endodermal tissue. Yet, increasing evidence indicates that LRH‐1, although expressed at low levels, is also a critical regulator of the hematopoietic system. LRH‐1 regulates the immune system by contributing to immune cell‐specific functions.
Lukas Meisinger +3 more
wiley +1 more source
Impaired Knee Joint Position Sense in Chronic Patellar Tendinopathy Is Associated with Kinesiophobia but Not Central Sensitization. [PDF]
Yener Ö, Karatepe AG.
europepmc +1 more source
Chromosomal DNA double‐strand breaks (DSBs) are repaired by homologous recombination and nonhomologous end joining (NHEJ). Recent work has additionally established theta‐mediated end‐joining (TMEJ) as a mechanism for DSB joining. Cells lacking NHEJ and TMEJ can repair DSBs in a homology‐dependent manner.
Shinta Saito +6 more
wiley +1 more source
Rescue by Hypothermic Oxygenated Machine Perfusion for Unexpected Long Prolongation of Cold Preservation Time in Expanded Criteria Donor Kidneys Can Achieve Favorable 2-Year Outcomes. [PDF]
Mingozzi S +16 more
europepmc +1 more source
The C. elegans Shu complex (RFS‐1/RIP‐1/SWS‐1) is a DNA‐dependent ATPase that regulates RAD‐51 filaments during homologous recombination. The trimer preferentially binds 5′‐exposed DNA, remodels RAD‐51 filaments via ATP hydrolysis, and stabilizes filaments through ATP binding.
Sam Siu Hang Chu +4 more
wiley +1 more source
Exploring Current Procedural Terminology Codes for Physical Therapist Evaluations in the United States: Results of a Feasibility Study. [PDF]
Rethman KK +6 more
europepmc +1 more source
CD36‐mediated lipid rewiring in the metabolic adaptation of tumour ecosystems
Nutrient deprivation drives a lipid‐centric shift in tumour metabolic symbiosis and signalling network. CD36 functions as a bidirectional bridge, transferring fatty acids from stromal donors (adipocytes, CAFs) to the ecosystem tumour‐ and microenvironment‐dependently.
Anna Sebestyén +11 more
wiley +1 more source

