Results 201 to 210 of about 118,210 (303)

Evaluating evidence based options for initial PTSD treatment non-response: A randomized controlled trial protocol. [PDF]

Contemp Clin Trials Commun
Held P, Hutzler I, Warren M, Streubel O, Pridgen SA, Smith DL, Cloitre M, Rothbaum BO, Kaysen DL.   +8 more
europepmc   +1 more source

Deficiency of Mitochondrial Fatty Acid Enzyme, CPT1A, Underlies Airway Epithelial Barrier Dysfunction in Severe Asthma

Allergy, EarlyView.
Mitochondrial fatty acid enzyme, CPT1A, is deficient in the airway epithelium of severe asthma patients. Restoration of CPT1A expression improved epithelial barrier integrity via increasing mitochondrial respiration and ATP production in airway epithelial cells. Restoration of deficient epithelial CPT1A may represent a new treatment approach for severe
Muyun Wang, Haiyang Hu, Kun Wang, Di Wu, Ximing Liao, Jing Gao, Tian Li, Wujian Xu, Shaoyong Gao, Qiang Li, Pankaj Kumar Bhavsar, Wei Gao, Kian Fan Chung   +12 more
wiley   +1 more source

Cooperative inhibition of mTORC1 disrupts iron-redox homeostasis and triggers ferritinophagy-dependent ferroptosis in hepatocellular carcinoma. [PDF]

Redox Biol
Chen X, Tan Z, Zhao S, Li F, Liu Y, Ren C, Li J, Lo H, Cui Y, Zhou A, Zhu C, Wu A, Jiang N, Ren F.   +13 more
europepmc   +1 more source

Distinct Immunometabolic Profiles in Finnish and Russian Karelian Adolescents With Contrasting Allergy Risk

Allergy, EarlyView.
We compared Finnish and Russian Karelian adolescents with contrasting allergy burden using integrated proteomic, metabolomic, and transcriptomic profiling. Finnish adolescents showed a broader pro‐inflammatory PBMC secretory profile consistent with a low‐grade inflammatory phenotype.
Nanna Fyhrquist, Matilda Riskumäki, Piia Karisola, Anni Nieminen, Tiina Laatikainen, Hanna Sinkko, Laura Paalanen, Pekka Jousilahti, Erkki Vartiainen, Mika J. Mäkelä, Tari Haahtela, Harri Alenius   +11 more
wiley   +1 more source

Research to real-world impact: evidence-based knowledge mobilization to improve support for UK women veterans who have experienced military sexual trauma. [PDF]

Eur J Psychotraumatol
Dryden D, Campbell GM, Murphy D.
europepmc   +1 more source

Factors for Success and Failure of Allergen Immunotherapy (AIT) Trial Design in the Light of Evidence‐Based Medicine: Current Aspects 2026

Allergy, EarlyView.
ABSTRACT Allergen immunotherapy (AIT) has been acknowledged as the only disease‐modifying treatment for respiratory diseases since its introduction in 1911. Although the efficacy and safety have convincingly been established in numerous randomized clinical trials (RCTs), the AIT study results may vary substantially.
Roy Gerth van Wijk, Vera Mahler, Melanie Albrecht, Danilo di Bona, Benjamin Hofner, Jasper Kappen, Susanne Kaul, Graham Roberts, Mohamed H. Shamji, Stefan Vieths, Oliver Pfaar   +10 more
wiley   +1 more source

Association of Real-Time Glucose Levels and Cognitive Performance in Children with Type 1 Diabetes: A Cross-Sectional Study. [PDF]

J Clin Med
Wais P, Stanisławska-Kubiak M, Niechciał E, Fichna P, Kędzia A, Mojs E, Majewska KA.   +6 more
europepmc   +1 more source

Sugammadex vs. neostigmine and the risk of postoperative pulmonary complications after upper gastrointestinal endoscopic procedures: a propensity score matched analysis of 15,730 patients

Anaesthesia, EarlyView.
Summary Introduction Postoperative pulmonary complications after upper gastrointestinal endoscopic procedures under general anaesthesia are clinically important and may be exacerbated by residual neuromuscular block. We evaluated whether antagonism of neuromuscular block with sugammadex rather than neostigmine is associated with improved respiratory ...
Yung‐Fong Tsai, Kuo‐Chuan Hung, Chih‐Yi Hsu, Huan‐Tang Lin, Yi‐Chen Lai, Shao‐Chun Wu   +5 more
wiley   +1 more source

Beyond Traditional Continuous Performance Tests: The Incremental Diagnostic Value of Distractor-Embedded Paradigms. [PDF]

Psychiatry Investig
Kılınçel Ş, Bulut F, Kılınçel O.
europepmc   +1 more source