Results 181 to 190 of about 118,210 (303)

Multi‐Target Pharmacological Mechanisms of Salvia miltiorrhiza Bunge in Metabolic Syndrome and Cardiovascular Diseases: A Comprehensive Review Based on the Theory of “Same Treatment for Different Diseases”

open access: yesPhytotherapy Research, EarlyView.
Salvia miltiorrhiza Bunge in metabolic syndrome and cardiovascular diseases: multi‐target actions on shared signaling pathways. ABSTRACT Metabolic syndrome (MetS) represents a clinical disorder characterized by the clustering of conditions including obesity, elevated blood sugar levels, and high lipid levels, which are intricately linked to the onset ...
Zhiyi Jia   +6 more
wiley   +1 more source

A CD44-targeted PDA/ZnO redox-active nanocomposite that couples chemotherapy with mitochondrial stress and tumor immune remodeling. [PDF]

open access: yesJ Nanobiotechnology
E-Y Chuang A   +10 more
europepmc   +1 more source

Enhancing Tea Agrifood System Resilience Amid Geopolitical Tensions: A Resource Nexus‐Based System Dynamics Analysis

open access: yesSustainable Development, EarlyView.
ABSTRACT Geopolitical conflicts are increasingly threatening global food security, economic stability, and peace, impacting Tanzania's tea agrifood system. This study develops a quantitative Resource Nexus‐based system dynamics simulation model assessing the feedbacks and interdependencies among key environmental and socioeconomic resources shaping ...
Ally Mkumbukiy   +3 more
wiley   +1 more source

Combination of PARPi and topoisomerase I inhibitors is highly effective in olaparib-resistant ovarian cancer. [PDF]

open access: yesExp Hematol Oncol
Chiappa M   +10 more
europepmc   +1 more source

Equity‐Calibrated Technology Forecasting for Sustainable Development: A Portable ADOPT Framework Integrating Bayesian‐Ising Diagnostics

open access: yesSustainable Development, EarlyView.
ABSTRACT Climate‐smart agriculture (CSA) is widely promoted to enhance resilience and productivity among smallholder farmers, yet its diffusion remains uneven due to structural barriers and heterogeneous adoption contexts. Existing forecasting tools, such as the Adoption and Diffusion Outcome Prediction Tool (ADOPT), estimate adoption trajectories but ...
Denis Momanyi   +6 more
wiley   +1 more source

A lysosome‐targeted ultra‐sensitive viscosity probe for monitoring viscosity alterations during chemotherapy

open access: yesSmart Molecules, EarlyView.
A novel chemosensing platform based on a molecular rotor architecture is established for specific, dynamic detection of lysosomal viscosity. The platform allows real‐time tracking of lysosomal viscosity fluctuations induced by various chemotherapeutic agents, highlighting its significant potential as a powerful tool for early cancer diagnostics and ...
Haoyang Song   +6 more
wiley   +1 more source

Harnessing the nonthermal effects of ultrasound for cancer treatment: From mechanisms to applications

open access: yesSmart Molecules, EarlyView.
Nonthermal ultrasound transforms acoustic energy into diverse therapeutic bioeffects through cavitation, mechanical stimulation, and physicochemical activation. This review discusses how acoustic parameters, biological mechanisms, and responsive materials interact to influence nonthermal ultrasound‐enabled cancer therapies. Mechanism‐guided engineering
Liu Wang   +5 more
wiley   +1 more source

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