Results 41 to 50 of about 21,640 (247)

Circulating tumor DNA monitoring and blood tumor mutational burden in patients with metastatic solid tumors treated with atezolizumab

Molecular Oncology, EarlyView.
In patients treated with atezolizumab as a part of the MyPathway (NCT02091141) trial, pre‐treatment ctDNA tumor fraction at high levels was associated with poor outcomes (radiographic response, progression‐free survival, and overall survival) but better sensitivity for blood tumor mutational burden (bTMB).
Charles Swanton, Russell W. Madison, Candice Francheska B. Tambaoan, Funda Meric‐Bernstam, Christopher J. Sweeney, Razelle Kurzrock, Howard A. Burris III, David R. Spigel, Hanna Tukachinsky, Jason Hughes, Julia Malato, Bongin Yoo, Tania Szado, Cheryl Schwab, Lincoln W. Pasquina, Amaya Gasco, Katja Schulze, Claire F. Friedman   +17 more
wiley   +1 more source

Case for diagnosis Caso para diagnóstico

Anais Brasileiros de Dermatologia, 2013
Lichen sclerosus is a chronic inflammatory mucocutaneous disorder of unknown etiology that most commonly affects the female genitalia. Cutaneous involvement with nonhaemorrhagic bullous is very unusual.
Fernanda Guedes Lavorato, Natália Solon Nery, Lislaine Bomm, Danielle Mann, Alexandre Carlos Gripp, Maria de Fátima Guimarães Scotelaro Alves   +5 more
doaj  

Whose forests, whose voices? Mining and community- based nature conservation in southeastern Madagascar [PDF]

, 2012
This paper explores local experiences of private - sector led community - based nature conservation near Fort Dauphin, southeastern Madagascar through the analysis of a conservation zone managed in partnership between the Rio Tinto mining corporation ...
Kraemer, A
core   +3 more sources

Comparative single‐cell transcriptomic profiling of patient‐derived renal carcinoma cells in cellular and animal models of kidney cancer

FEBS Open Bio, EarlyView.
We generated and characterized clear cell renal cell carcinoma models using the patient‐derived RCC243 cell line—including cell culture, orthotopic, and metastatic tumors—via single‐cell RNA‐sequencing for comparisons between models and patient tumor datasets.
Richard Huang, Lynn Kee, Alexander Gont, Jalna Meens, Fraser G. Ferens, Meredith S. Irwin, Laurie Ailles, Scott A. Yuzwa, Claire M. Robinson, Michael Ohh   +9 more
wiley   +1 more source

Lobomycosis and squamous cell carcinoma Lobomicose e carcinoma espinocelular

Anais Brasileiros de Dermatologia, 2013
The occurence of squamous cell carcinoma on long-lasting ulcers is classic. Malignant transformation may occur on burn scars and chronic ulcers of varying etiology, including infectious agents. Transformation of old lobomycosis lesion scars into squamous
Lisiane Nogueira, Luciana Mendes, Carlos Alberto Chirano Rodrigues, Mônica Santos, Sinésio Talhari, Carolina Talhari   +5 more
doaj  

Biophysical characterization and ion transport with cell‐based and proteoliposome reconstitution assays of invertebrate K+‐Cl− cotransporters

FEBS Open Bio, EarlyView.
The K+‐Cl− cotransporters (KCCs) facilitate the symport of ions across the plasma membrane. They participate in physiological processes including neuronal regulation. Here, we characterized KCCs from Drosophila and Hydra vulgaris. Comparative analyses of transporters provide insights into the mechanism of KCC ion transport, regulation, and evolution ...
Satoshi Fudo, Marina Verkhovskaya, Coralie Di Scala, Claudio Rivera, Tommi Kajander   +4 more
wiley   +1 more source

Конструювання і дослідження математичних моделей. Модель пункту GPS спостережень. Частина 6 [PDF]

, 2009
При конструюванні математичної моделі в діапазоні від експериментальних (емпіричних) даних до істинної моделі, побудованої за способом найменших квадратів, розроблені автором методи конструювання дають можливість проводити підстройку в межах діапазону ...
Litnarovych, Ruslan Mykolaiovych, Литнарович, Руслан Николаевич, Літнарович, Руслан Миколайович   +2 more
core   +1 more source

Mineralogía y génesis de la fracción fina de la serie de El Rinconcillo (formaciones Flysch del Campo de Gibraltar. SW de España) [PDF]

, 1987
The stratigraphic sequence of El Rinconcillo belong to the Algeciras Unit. Illite, kaolinite, chlorite and interstratified illite-smectite are common minerals for materials of this Unit, but a high proportion of Fe-Al smectites and sporadic presence of ...
Carrasco, F., Rodríguez, P., Ruiz Cruz, M. D.   +2 more
core   +2 more sources

White Christian Nationalism: Adult Education and Threats to Democracy

New Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Adult education has a historical and ongoing commitment to fostering democratic relationships, demonstrated by the tendency of adult education to be called upon when social change and realignment are most desirable. This article considers the philosophical and pragmatic possibilities for adult education at this moment, when White Christian ...
Ralf St. Clair, Lyn Tett, Rob Black
wiley   +1 more source

Management of adverse events in patients with acute myeloid leukemia in remission receiving oral azacitidine: experience from the phase 3 randomized QUAZAR AML-001 trial

Journal of Hematology & Oncology, 2021
Background Most older patients with acute myeloid leukemia (AML) who attain morphologic remission with intensive chemotherapy (IC) will eventually relapse and post-relapse prognosis is dismal.
Farhad Ravandi, Gail J. Roboz, Andrew H. Wei, Hartmut Döhner, Christopher Pocock, Dominik Selleslag, Pau Montesinos, Hamid Sayar, Maurizio Musso, Angela Figuera-Alvarez, Hana Safah, William Tse, Sang Kyun Sohn, Devendra Hiwase, Timothy Chevassut, Francesca Pierdomenico, Ignazia La Torre, Barry Skikne, Rochelle Bailey, Jianhua Zhong, C. L. Beach, Herve Dombret   +21 more
doaj   +1 more source