Results 51 to 60 of about 785,950 (211)

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

open access: yesFEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta   +7 more
wiley   +1 more source

Small RNA pathways in mammalian oocytes

open access: yesFEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Constraints and/or determinants of return to sexual activity in the puerperium Condicionantes y/o determinantes del retorno a la actividad sexual en el puerperio Condicionantes e/ou determinantes do retorno à atividade sexual no puerpério

open access: yesRevista Latino-Americana de Enfermagem, 2013
OBJECTIVE: to identify factors which constrain or determine the return to sexual activity in the puerperium. METHOD: exploratory and descriptive study undertaken in a university hospital in the South of Brazil.
Cleci de Fátima Enderle   +5 more
doaj  

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

open access: yesFEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro   +1 more
wiley   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

open access: yesFEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

open access: yesFEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell   +8 more
wiley   +1 more source

First report of acariasis by Caparinia tripilis in African hedgehogs, (Atelerix albiventris), in Costa Rica Primeiro relato de acariasis por Caparinia tripilis em ouriços Africanos, (Atelerix albiventris), na Costa Rica

open access: yesRevista Brasileira de Parasitologia Veterinária, 2013
The African hedgehog is one of the newly imported exotic pets which have been observed with increasing regularity in veterinary clinics in Costa Rica. Despite their popularity, information about their diseases is scarce. Within skin diseases of hedgehogs,
Andrés Moreira   +2 more
doaj  

Caracterización geoquímica de los depósitos alimentados por fuentes de lava del volcán Las Herrerías (Región Volcánica del Campo de Calatrava, Ciudad Real)

open access: yesEstudios Geologicos, 2014
El volcán Las Herrerías (Bolaños de Calatrava; Región Volcánica del Campo de Calatrava) se caracteriza por una gran cantidad y variedad de depósitos originados a partir de fuentes de lava.
F. Sarrionandia   +3 more
doaj   +1 more source

Adenosine triphosphate as a modulator of protein interactions and stability

open access: yesFEBS Open Bio, EarlyView.
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley   +1 more source

Využívání otevřených vzdělávacích zdrojů studenty environmentálních oborů v České republice

open access: yesEnvigogika, 2018
Otevřené vzdělávací zdroje (OER) jsou důležitou inovací ve vzdělávacích technologiích. Jejich správné využívání může mít řadu benefitů pro vysokoškolské vzdělávání i v oblasti environmentálního vzdělávání.
Eduard Petiška
doaj   +1 more source

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