Results 41 to 50 of about 2,027,004 (245)
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
L’OBJET INFINITIVAL REVISITE : APPORT DE L’OPPOSITION SEMANTIQUE AFFECTÉ / EFFECTUÉ [PDF]
Studii si Cercetari Filologice: Seria Limbi Romanice, 2008 Cette étude porte sur les constructions transitives directes des verbes aspectuels, dont l’objet direct nominal peut être mis en correspondance avec un objet infinitival. Nous discutons la solution proposée par G.
Florinela COMANESCU
doaj
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Captation spéculaire et mise en abyme dans le film Jane Eyre de Franco Zeffirelli
Revue LISA, 2009 This article presents Franco Zeffirelli’s baroque use of mirrors to evoke the specular alienation of Jane Eyre who is both the heroine and the story-teller in the movie and in the original text.
Isabelle Van Peteghem-Tréard
doaj +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
La convergence des propositions
Percées, 2020 Les résultats de recherche présentés dans cet article concernent la première phase d’un processus de création. Ils sont issus d’une démarche de théorisation empirique et inductive (la « grounded theory » de Glaser et Strauss, 1967; Strauss et Corbin ...
Marie-Josée Plouffe
doaj +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Le souffle de l’histoire chez Georgette LeBlanc
Voix Plurielles, 2016 Cet article porte sur le dialogue entre temps vécu et temps de l’histoire dans les quatre « romans poétiques » de l’auteure acadienne Georgette LeBlanc, étude qui s’appuie sur la parution récente du Grand feu (2016).
Julie St-Laurent
doaj