Results 51 to 60 of about 2,027,004 (245)

Creation and analysis of biochemical constraint-based models: the COBRA Toolbox v3.0

Nature Protocols, 2019
Constraint-based reconstruction and analysis (COBRA) provides a molecular mechanistic framework for integrative analysis of experimental molecular systems biology data and quantitative prediction of physicochemically and biochemically feasible phenotypic
Laurent Heirendt, Sylvain Arreckx, Thomas Pfau, Sebastián N. Mendoza, A. Richelle, A. Heinken, Hulda S. Haraldsdóttir, J. Wachowiak, Sarah M. Keating, Vanja Vlasov, Stefanía Magnúsdóttir, C. Ng, German Preciat, Alise Zagare, S. H. Chan, Maike K. Aurich, Catherine M. Clancy, J. Modamio, John T. Sauls, A. Noronha, A. Bordbar, Benjamin R. Cousins, Diana C. El Assal, L. Valcárcel, Iñigo Apaolaza, Susan Ghaderi, Masoud Ahookhosh, Marouen Ben Guebila, A. Kostromins, Nicolas Sompairac, Hoai M. Le, Ding Ma, Yuekai Sun, Lin Wang, James T. Yurkovich, Miguel A. P. Oliveira, P. Vuong, Lemmer R. P. El Assal, I. Kuperstein, A. Zinovyev, H. S. Hinton, W. Bryant, F. J. Aragón Artacho, F. J. Planes, E. Stalidzans, A. Maass, S. Vempala, M. Hucka, M. Saunders, C. Maranas, N. Lewis, T. Sauter, B. Palsson, I. Thiele, R. Fleming   +54 more
semanticscholar   +1 more source

Deep learning for deepfakes creation and detection: A survey [PDF]

Computer Vision and Image Understanding, 2019
Deep learning has been successfully applied to solve various complex problems ranging from big data analytics to computer vision and human-level control.
T. Nguyen, Q. Nguyen, Dung Nguyen, D. Nguyen, Thien Huynh-The, S. Nahavandi, T. Nguyen, Quoc-Viet Pham, Cu Nguyen   +8 more
semanticscholar   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Erasing Memory and Trauma in Mark Ravenhill and David Chisholm’s The Experiment. The effort of remembering, or how to not fall into oblivion through the use of vestigial forms in contemporary contexts

Resonancias, 2021
Mauricio Carrasco
doaj   +1 more source

L’usage du xylophone djomlo : du patrimoine musical ancestral à la création artistique contemporaine adaptée aux nouveaux courants musicaux [PDF]

GRALIFAH
La question de la transmission-sauvegarde des savoirs ancestraux est aujourd’hui une préoccupation fondamentale pour la souveraineté des peuples africains.
ATTOUNGBRE Kouadio Félix
doaj  

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Poèmes

Voix Plurielles, 2013
Poèmes
Sonia Lamontagne
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source