Results 81 to 90 of about 1,093,718 (242)

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

Technologie et création artistique

open access: yes, 1981
National audienceCe texte porte sur les recherches menées par l'Acroe, c'est-à-dire sur le rôle des technologies contemporaines dans les pratiques culturelles, en particulier dans le domaine de la création musicale, et sur la volonté d'y apporter une ...
Cadoz, Claude
core   +1 more source

Establishing a Regional AIS Application Specific Message Register [PDF]

open access: yes, 2010
The goal of the Regional AIS Application Specific Message Register is to provide awareness of what applications exist, facilitate harmonization, and promote proper binary messaging for regional applications. To be hosted on the IALA website, establishing
Alexander, Lee   +2 more
core   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

ong et Développement Agricole Au Burkina Faso: Présence Majeure et Effets Mineurs [PDF]

open access: yes, 1994
This report analyses the effect of NGO participation on Agriculture ...
Alain Piveteau
core  

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Apprendre à traverser les murs. La Cocinchine

open access: yesVoix Plurielles, 2012
Amprimoz, Alexandre ...
Alexandre Amprimoz
doaj  

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

L’éthique dans la conception publicitaire [PDF]

open access: yesRevue de l'UKA
Cet article attire l’attention sur les principes moraux qu’il faut prendre en compte dans la conception des messages publicitaires. Les agissements et les pratiques qui portent atteinte aux normes éthiques en publicité, sont ici critiqués, tout en ...
Isaac TSHINDUMBA TSHIKOTA
doaj  

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