Results 21 to 30 of about 621,353 (193)
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Preparation of Magnetic Coal-measure Kaolinite Nanomaterials and Adsorption of Cr(Ⅵ) [PDF]
This is an article in the field of mineral materials. In order to develop the high-value utilization technology of coal associated mineral resources kaolinite, coal-measure kaolinite nanomaterials(CKN) were prepared by indirect intercalation-liquid phase
Xianshu DONG +4 more
core +1 more source
ChrR Gene Variability in Cr-stressed Leptolyngbya boryana for the Biotransformation of Cr (VI) to Cr (III) [PDF]
, 2023 Chromium (VI) is a well-known pollutant that is present in industrially polluted soil and water, and has been reported to be mutagenic and carcinogenic.
Vinay Dwivedi +3 more
core +1 more source
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
Effects of Heavy Metal Cr（Ⅵ）on the Growth and Ecophysiology of Mangrove Avicennia marina Seedlings [PDF]
, 2008 采用砂基栽培，研究重金属Cr(Ⅵ)在不同浓度梯度和不同胁迫处理阶段（种苗期和幼苗期）及胁迫处理时间条件下对红树植物白骨壤（Avicenniamarina）幼苗的生长及生理生态效应的影响。设置Cr(Ⅵ)胁迫浓度系列为1.0、2.5、5.0、7.5、10.0、15.0、20.0mg·L-1，以不加Cr(Ⅵ)为对照，培养基海水盐度均为15‰，培养期分为45d和150d。实验期间全程记录及观测各胁迫组白骨壤种苗萌发及幼苗生长状况，定期记录幼苗的高度生长、叶片大小 ...
万永吉
core
Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
carnotresearch/cr-nimble: CR-Nimble v0.2.4
, 2022 Added Digital signal processing utilities moved from cr-sparse to cr-nimble Moved discrete number related functions from cr-sparse. Some sparse vector and matrix processing functionality moved from cr-sparse.
Shailesh Kumar
core +1 more source