Results 41 to 50 of about 602,331 (198)

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source

ANALYSIS ON THE FACTORS AFFECTING CAPITAL STRUCTURE ON FOOD AND BEVERAGE COMPANIES IN IDX

BAKI (Berkala Akuntansi dan Keuangan Indonesia), 2020
Capital structure is related with company funding. This study aims to examine and analyze the factors that influence the capital structure of food and beverage companies listed on the Indonesia Stock Exchange.
Rani Milansari, Endang Masitoh, Purnama Siddi   +2 more
doaj   +1 more source

ESR1 methylation and ESR1 mutations in circulating tumor cells (CTCs) and paired plasma‐cfDNA of advanced breast cancer patients: A feasibility proof‐of‐concept study

Molecular Oncology, EarlyView.
Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou, Athina Markou, Eleonora Nicolo, Mara S Serafini, Qiang Zhang, Youbin Zhang, Lorenzo Gerratana, Andrew A. Davis, Huiping Liu, William J Gradishar, Carolina Reduzzi, Massimo Cristofanilli, Evi Lianidou   +12 more
wiley   +1 more source

Determination of chromium valence state in the CaO–SiO2–FeO–MgO–CrOx system by X-ray photoelectron spectroscopy

High Temperature Materials and Processes, 2020
The chromium valence states in the CaO–SiO2–FeO–MgO–CrOx system were investigated by X-ray photoelectron spectroscopy (XPS). The results indicated that the XPS peaks of Cr 2p3/2 and Cr 2p1/2 locate at the binding energy of ∼577 and ∼586 eV, respectively.
Liu Deman, Diao Jiang, Qiu Yiyu, Wang Guang, Li Gang, Xie Bing   +5 more
doaj   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

Molecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski, Júlia Perera‐Bel, Alejo Rodriguez‐Vida, Nuria Juanpere, Jihyun Lee, Daniel E. Michaud, Jennifer L. Guerriero, Kent W. Mouw, Aristotelis Bamias, Filipe L. F. Carvalho, Joaquim Bellmunt   +10 more
wiley   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Comparative Study on Monolithic Zirconia and Lithium Disilicate

Journal of Pharmacy and Bioallied Sciences
Background: In recent years, patient awareness and demands for dental aesthetic have increased tremendously. Aim: To compare between MZ and DL for SR and CR. Material and Method: A total of 64 samples were included and divided into two groups, i.e. A and
Anup Patil, Manish R. Bhise, Shivsharan Dhadde, Lishoy W. Rodrigues, Pratiksha Jadhav, Pushkar Gupta   +5 more
doaj   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Analyzing the dynamics of changes in demand, production, and cost for lead, tin and chromium

Литьë и металлургия
Developments in electronics and electronic device manufacturing technologies including smartphones, computers and electric cars are significantly affecting demand.
A. S. Panasyugin, N. P. Masherova, I. A. Pankovets, S. V. Martseva, N. D. Pavlovsky   +4 more
doaj   +1 more source

Comparison Study of Time Synchronization in NC-OFDM Systems Based on Symmetric Correlator

Jurnal Elektronika dan Telekomunikasi, 2019
NC-OFDM as one of the candidates for the Cognitive Radio (CR) system has many challenges in the synchronizing time. This is due to the frequency sharing which can cause Narrowband Interference (NBI), which causes a very significant time synchronization ...
Tajul Miftahushudur, Suyoto Suyoto
doaj   +1 more source