Results 51 to 60 of about 3,388,611 (277)
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background/Objectives Outcomes for pediatric relapsed/refractory (R/R) acute myeloid leukemia (AML) remain dismal. CPX‐351, a liposomal formulation of cytarabine and daunorubicin, may have less off‐target toxicities than traditional chemotherapies and has shown improved outcomes for adults with newly diagnosed therapy‐related AML.
Jonathan D. Bender +17 more
wiley +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Purpose Malignant rhabdoid tumor of the kidney (MRTK) is a rare, aggressive tumor seen in young children. The optimal timing of resection for locally advanced tumors is not well‐defined. The purpose of this study is to evaluate modern oncologic outcomes and the impact of surgical timing. Methods A multicenter retrospective review was performed
Hannah N. Rinehardt +76 more
wiley +1 more source
PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Yankuang ceshi, 2014 A microwave digestion method to simultaneously determine V, Cr, Ni, Ge and As in geochemical samples by Inductively Coupled Plasma-Mass Spectrometry (ICP-MS) is proposed.
SHEN Yu +4 more
doaj +2 more sources
Spectrum of cosmic rays, produced in supernova remnants
, 2007 Nonlinear kinetic theory of cosmic ray (CR) acceleration in supernova remnants is employed to calculate CR spectra. The magnetic field in SNRs is assumed to be significantly amplified by the efficiently accelerating nuclear CR component. It is shown that
Bell A. R. +8 more
core +1 more source
Stabilization of Cr(III) wastes by C3S and C3S hydrated matrix : comparison of two incorporation methods [PDF]
, 2015 In the present study, the influence of Cr(III) on the properties of C3S and its stabilization in C3S hydrates was investigated by either direct incorporation as Cr2O3 during C3S preparation or introduced as nitrate salt during hydration.
De Schutter, Geert +3 more
core +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Journal of Management and Business ReviewThe condition of the Indonesian economy, which is currently unstable due to the COVID-19 pandemic situation, has had an impact on sub-sector companies, especially property and real estate sub-sector companies. The impact felt by companies in the property
Azka Halimah Nur Arnita, Ida Ida
doaj +1 more source
, 2012 There are only some exceptional CR dimensions and codimensions such that the geometries enjoy a discrete classification of the pointwise types of the homogeneous models.
A. Čap +10 more
core +2 more sources