Results 211 to 220 of about 71,609 (291)
Redirecting a Fungal Quercetin 2,3‐Dioxygenase Toward Artificial Flavonols
A novel quercetin 2,3‐dioxygenase was engineered to reshape its substrate‐binding cavity and redirect its specificity toward artificial flavonols. One variant with a larger substrate‐binding cavity exhibited 20‐ to 1750‐fold higher activity toward bulky flavonols with phenyl‐based substitutions at position C‐8.
Michael Kotik +9 more
wiley +1 more source
Recent clinical advances in fibroblast activation protein targeted radioligand therapy for solid tumors. [PDF]
Wu X, Wang Y, Li Y, Hu W.
europepmc +1 more source
A tetracarbonyl tungsten complex bearing a bis‐triazolylidene ligand exhibits excellent catalytic activity in the acceptorless dehydrogenative coupling of 1‐phenylethanol and 2‐aminobenzyl alcohol to form 2‐phenylquinoline with H2 evolution. Mechanistic investigations combining experimental and DFT studies reveal the unprecedented base‐promoted ...
Beatriz Garcia +2 more
wiley +1 more source
Understanding the influence of marine nutrients on insectivorous and herbivorous reptiles in the Gulf of California islands. [PDF]
Barraza-Soltero IK +4 more
europepmc +1 more source
We present an accessible plunge‐freezing and freeze‐drying workflow for preparing adherent mammalian cells for synchrotron‐based nanofocused X‐ray fluorescence (XRF) microscopy and X‐ray absorption spectroscopy (XAS), enabling sub‐micron mapping of metal distribution and chemical speciation.
Joaquin Tamargo‐Azpilicueta +8 more
wiley +1 more source
Multiple formation pathways for amino acids in the early Solar System based on carbon and nitrogen isotopes in asteroid Bennu samples. [PDF]
Baczynski AA +11 more
europepmc +1 more source
Abstract Eastern populations of monarch butterflies (Danaus plexippus) overwinter in the central trans‐volcanic belt of Mexico, relying primarily on lipids accumulated during migration to sustain this several‐month‐long overwintering period. This study shows how drought conditions in north‐central Mexico influenced lipid dynamics in monarchs ...
Libesha Anparasan +5 more
wiley +1 more source
Appraisal of groundwater susceptibility to pollution using hybrid framework of stable isotopes and indexed approach. [PDF]
Hagagg K, Sirag NM.
europepmc +1 more source
Charnockites with 2691–2607 Ma magmatic ages from the NMZ show arc‐magmatic geochemical signatures. They correspond to the lower‐crustal equivalent of the Chilimanzi Suite Granite in the Zimbabwe Craton. Lu‐Hf isotopic data of magmatic zircons show negative εHf(t) values (−11.18 to −2.20) with TDMC ages of 3699–3158 Ma, suggesting their protolith ...
Toshiaki Tsunogae +6 more
wiley +1 more source
The variety and origin of materials accreted by Bennu's parent asteroid. [PDF]
Barnes JJ +86 more
europepmc +1 more source

