Results 81 to 90 of about 1,865,203 (286)

Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy

Molecular Oncology, EarlyView.
LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir, Elena Haro‐Martínez, Sandra Blasco‐Benito, Chiara Cannatà, José Ángel Palomeque, Anna López‐Plana, Maria Sanz‐Flores, Marc Sabartés, Cristina Fornaguera, Toni Celià‐Terrassa   +9 more
wiley   +1 more source

Hexavalent chromium induces ferroptosis in small intestinal tissue of broilers through GPX4/HMGB1/p38-MAPK pathway

Poultry Science
As a major environmental heavy metal pollutant, hexavalent chromium (Cr(VI)) causes irreversible damage to animals and humans. Nevertheless, how Cr(VI) exposure causes intestinal damage in broilers remains inadequately explored. This study explores Cr(VI)
Juezhang Wang, Bingtong Fan, Weina Liu, Zibo Ma, Ruiqin Guo, Jinhang Guo, Jinglu Wang, Ding Zhang, Zilong Sun, Ci Liu   +9 more
doaj   +1 more source

Comparison of the Performance of Chlorococcum Ellipsoideum and Tetradesmus Obliquus as a Carbon Source for Reduction of Cr(VI) with Bacteria

Chemical Engineering Transactions, 2018
Chromium (Cr) is used in a variety of metallurgical, refractory and chemical processes, as well as in industrial activities such as the refining of ore, the production of steel and alloys, metal plating, and tanneries.
Maria M. Roestorff, Evans M. N. Chirwa
doaj   +1 more source

Small RNA pathways in mammalian oocytes

FEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Development of a Fast Method Using Inductively Coupled Plasma Mass Spectrometry Coupled with High-Performance Liquid Chromatography and Exploration of the Reduction Mechanism of Cr(VI) in Foods

Toxics
Hexavalent chromium (Cr(VI)) is known as the most hazardous species of chromium. Speciation analysis of Cr in foods is of a great significance for assessing its influences on human health. In this study, a fast HPLC-ICP-MS method for the determination of
Ge Song, Honglian Tan, Chuhan Cheng, Peng Li, Xinyang Sun, Yuling Zhou, Yong Fang   +6 more
doaj   +1 more source

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

FEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro, Fernando Lucas Palhano   +1 more
wiley   +1 more source

Especiação redox de cromo em solo acidentalmente contaminado com solução sulfocrômica Crhomium redox specification in soil accidentally contamined with sulphochrinuc solution

Química Nova, 2008
Determination of Cr(VI) and Cr(III) was studied in soil samples accidentally contaminated with sulphochromic solution. Molecular absorption spectrophotometry based on the diphenylcarbazide method was used for the determination of Cr(VI) after its ...
Wladiana Oliveira Matos, Joaquim de Araújo Nóbrega, Gilberto Batista de Souza, Ana Rita Araujo Nogueira   +3 more
doaj   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

ADSORPTION OF Cr(VI) ON BLACK WATER [PDF]

, 2010
The effect of initial concentration of Cr(VI) on adsorption to black water of Gambut, District of Banjar, South Borneo has been investigated, as well as interaction between Cr(VI) species and functional black water organic fraction.
Herdiansyah Herdiansyah, Rasti Januarita
core   +1 more source

Evaluation of Cr(VI) Reducing Capability of Shewanella putrefaciens (MTTC8410) and Optimization of Operational Parameters

Journal of Pure and Applied Microbiology, 2020
Bioremediation is an important technology to remediate the chromium (Cr) contaminated soil and water. In this study, Shewanella putrefaciens (MTTC8410) was used to investigate the influence of carbon concentration, pH, and temperature on reduction of ...
Annadurai Sakthi Thesai, Rajalingam Sangeetha, Lakshmanan Ashokkumar, Ramachandran Palanivelan, Sundaram Rajakumar, Pudukadu Munusamy Ayyasamy   +5 more
doaj   +1 more source