Results 61 to 70 of about 1,865,203 (286)

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

Spectroscopic Investigation of Cr(III)- and Cr(VI)-Treated Nanoscale Zerovalent Iron

open access: yes, 2016
The reaction of hexavalent chromium (Cr(VI)) with zerovalent iron (Fe0) during soil and groundwater remediation is an important environmental process.
Sushil Raj Kanel (2510263)   +3 more
core   +1 more source

Removal of hexavalent chromium by a microbial mat from a mining site under anaerobic conditions

open access: yesFrontiers in Bioengineering and Biotechnology
Mining activities have contributed to increased contamination of groundwater with hexavalent chromium (Cr(VI)). Microbial mats have been shown to effectively remove Cr(VI) under aerobic conditions, however, their role in Cr(VI) removal under anaerobic ...
Mohammad Tariq Ali Khan   +3 more
doaj   +1 more source

Microbial Reduction of Chromate in the presence of Nitrate by Three Nitrate Respiring Organisms.

open access: yesFrontiers in Microbiology, 2012
A major challenge for the bioremediation of toxic metals is the co-occurrence of nitrate, as it can inhibit metal transformation. Geobacter metallireducens, Desulfovibrio desulfuricans, and Sulfurospirillum barnesii are three soil bacteria that can ...
Peter eChovanec   +6 more
doaj   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

Photoredox processes in the Cr(VI)-Cr(III)-oxalate system and their environmental relevance

open access: yes, 2005
Irradiation of the $[Cr(C_{2}O_{4})_{3}]^{3-}$ complex or the chromate(VI)-oxalate mixture, or the ternary system composed of Cr(III), Cr(VI) and oxalate, leads to chromium photoreductions in consequence of the ligand to metal charge transfer (LMCT ...
Mytych, Piotr   +2 more
core   +1 more source

In Situ Bioremediation of Chromium (VI) In a Simulated Ferrochrome Slag

open access: yesChemical Engineering Transactions, 2017
Stability of chromium in the tailing dumps and stockpiles of chromium concentrate at chrome mining fields is affected by pH, redox potential, and the presence of other metallic species in the waste rocks. It is desirable to keep chromium in the dump site
N. Bansal, J.J. Coetzee, E.M.N. Chirwa
doaj   +1 more source

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

open access: yesMolecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee   +3 more
wiley   +1 more source

Biotransformation of Cr (VI) by Newly Invented Bacterial Consortium SN6

open access: yes, 2018
Extensive use of hexavalent chromium in various industrial processes and improper treatment technology for remediation has laid serious public health problems.
Nikhil Bhatt, Suchi Dave
core   +1 more source

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