Association of CHRNA5 Gene Variants with Crack Cocaine Addiction
Genome-wide studies provide increasing evidence of association of genetic variants with different behaviors. However, there is a growing need for replication and subsequent characterization of specific findings.
A. Aroche +9 more
semanticscholar +1 more source
AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury
Hepatology, EarlyView.
Robert J. Fontana +6 more
wiley +1 more source
Butyrylcholinesterase Genetic Variants: Association with Cocaine Dependence and Related Phenotypes [PDF]
Objective: the search for genetic vulnerability factors in cocaine dependence has focused on the role that neuroplasticity plays in addiction. However, like many other drugs, the ability of an individual to metabolize cocaine can also influence ...
Guindalini, Camila +6 more
core +3 more sources
Clinical periodontal diagnosis
Abstract Periodontal diseases include pathological conditions elicited by the presence of bacterial biofilms leading to a host response. In the diagnostic process, clinical signs such as bleeding on probing, development of periodontal pockets and gingival recessions, furcation involvement and presence of radiographic bone loss should be assessed prior ...
Giovanni E. Salvi +5 more
wiley +1 more source
Molecular Cages as Probes in Indicator Displacement Assays: The Case of Scopolamine Detection
In this research, we show the concept of molecular cages as probes in indicator displacement assays, focusing on scopolamine detection, a drug often used in drug‐facilitated sexual assaults. Drug sensing occurs via the drug‐induced transformation of non‐emissive [Fluorescein2⊂Cage] complex into [Scopolamine⊂Catenane] and highly emissive free ...
Giovanni Montà‐González +5 more
wiley +2 more sources
A Study to Validate a Self-Reported Version of the ONS Drug Dependence Questionnaire [PDF]
Aim: A prospective study to establish the reliability of a self-completion version of the Office for National Statistics (ONS) questionnaire for assessing drug dependence of substance misuse clients.
Christo G. +17 more
core +1 more source
Frequency, factors and costs associated with injection site infections: findings from a national multi-site survey of injecting drug users in England. [PDF]
BACKGROUND: Injection site infections among injecting drug users (IDUs) have been associated with serious morbidity and health service costs in North America.
Hickman, Matthew +4 more
core +3 more sources
Adulterants in crack cocaine in Brazil.
INTRODUCTION Brazil is the world's biggest consumer of crack cocaine, and dependence is a major public health issue. This is the first study to investigate the prevalence of potentially harmful adulterants present in hair samples from Brazilian patients ...
M. Ribeiro +10 more
semanticscholar +1 more source
Crack-cocaine in São Paulo: accessibility, market strategies and ways of use [PDF]
BACKGROUND: In Brazil, survey data have pointed to an increase in crack cocaine lifetime use, possibly due to changes on its accessibility, market strategies and ways of use.
Nappo, Solange Aparecida +1 more
core +3 more sources
Immunotoxicity of Cocaine and Crack
The toxicity of cocaine and crack was studied on the protozoan Tetrahymena pyriformis, using several endpoints, such as the DNA content of the macronuclei and the phagocytic ability. Both forms induced an increase in the DNA content of the protozoan, which indicates the stimulation of the mitotic process.
Stefanidou, M. +3 more
openaire +3 more sources

