Results 21 to 30 of about 4,963 (266)
Transactions of Nanjing University of Aeronautics and AstronauticsTo investigate the residual stress distribution and its influence on machining deformation in 6061‑T651 aluminum alloy plates， this paper uses the crack compliance method to study the residual stress characteristics of 6061-T651 aluminum alloy plates ...
HE Wenbo +4 more
doaj +1 more source
Composites Part C: Open Access, 2023 Damage modelling of composite material delamination is an intense field of research to understand the complex composite failure behaviour and predict the residual strength of damaged structures. One of the widely employed methods to simulate delamination
Heng (Hannah) Liu +4 more
doaj +1 more source
Numerical Evaluation of the Crack Compliance Method (CCM) in Beams with and without Prior History [PDF]
Applied Mechanics and Materials, 2008 This work assesses the Crack Compliance Method (CCM), which has been extensively used for the experimental evaluation of residual stresses, by the Finite Element Method (FEM) to validate its experimental applicability through numerical evaluation.
G. Urriolagoitia-Sosa +6 more
openaire +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Molecular Oncology, EarlyView.Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
Crack propagation in micro-chevron-test samples of direct bonded silicon-silicon wafers
Fracture and Structural Integrity, 2013 Wafer bonding describes all technologies for joining two or more substrates directly or using certain intermediate layers. Current investigations are focused on so-called low temperature bonding as a special direct bonding technology.
K. Vogel +5 more
doaj +3 more sources
Quantifying nonlinear fracture parameters in bituminous SCB specimens: A compliance-based approach
Case Studies in Construction MaterialsBituminous mixtures containing various defects, such as cracks and voids, exhibit ductile behavior in hot environments and brittle behavior in cold environments.
Ragip Ince, Erkut Yalcin, Mehmet Yilmaz
doaj +1 more source
Molecular Oncology, EarlyView.Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece +18 more
wiley +1 more source
Molecular Oncology, EarlyView.CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir +12 more
wiley +1 more source
Metals, 2022 The emerging wire + arc additive-manufacturing (WAAM) technique has significant potential to improve material design, as well as manufacturing cost and efficiency of structural components such as offshore wind turbines and subsequently reduce the ...
Anna Ermakova, Ali Mehmanparast
doaj +1 more source