Results 31 to 40 of about 19,445 (266)

Multi-Scale Crack Detection and Quantification of Concrete Bridges Based on Aerial Photography and Improved Object Detection Network

Buildings
Regular crack detection is essential for extending the service life of bridges. However, the image data collected during bridge crack inspections are complex to convert into physical information and construct intuitive and comprehensive Three-Dimensional
Liming Zhou, Haowen Jia, Shang Jiang, Fei Xu, Hao Tang, Chao Xiang, Guoqing Wang, Hemin Zheng, Lingkun Chen   +8 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Edge-Enhanced CrackNet for Underwater Crack Detection in Concrete Dams

Applied Sciences
Underwater crack detection in dam structures is of significant importance to ensure structural safety, assess operational conditions, and prevent potential disasters. Traditional crack detection methods face various limitations when applied to underwater
Xiaobian Wu, Weibo Zhang, Guangze Shen, Jinbao Sheng   +3 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Crack image detection based on fractional differential and fractal dimension

IET Computer Vision, 2019
In civil engineering, crack detection using image processing has gained much attention among researchers and transportation agencies. As the crack image often presents a fuzzy boundary and random shape, it is difficult to achieve satisfactory detection ...
Ting Cao, Weixing Wang, Susan Tighe, Shenglin Wang   +3 more
doaj   +1 more source

Detection Based on Crack Key Point and Deep Convolutional Neural Network

Applied Sciences, 2021
Based on the features of cracks, this research proposes the concept of a crack key point as a method for crack characterization and establishes a model of image crack detection based on the reference anchor points method, named KP-CraNet. Based on ResNet,
Dejiang Wang, Jianji Cheng, Honghao Cai
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source