Stress intensity factors for deep cracks emanating from the corner formed by a hole intersecting a plate surface [PDF]
A technique consisting of freezing photo-elasticity and a numerical method was used to obtain stress intensity factors for natural cracks emanating from the corner at which a hole intersects a plate surface.
Mcgowan, J. J., Smith, C. W.
core +1 more source
Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance
Aging and Cancer, EarlyView.NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang +3 more
wiley +1 more source
A Literature Review of Incorporating Crack Tip Plasticity into Fatigue Crack Growth Models. [PDF]
Materials (Basel), 2023 Garcia-Gonzalez A +4 more
europepmc +1 more source
Age‐Related Characteristics of SYT1‐Associated Neurodevelopmental Disorder
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objectives We describe the clinical manifestations and developmental abilities of individuals with SYT1‐associated neurodevelopmental disorder (Baker‐Gordon syndrome) from infancy to adulthood. We further describe the neuroradiological and electrophysiological characteristics of the condition at different ages, and explore the associations ...
Sam G. Norwitz +3 more
wiley +1 more source
Intrinsic Fatigue Limit and the Minimum Fatigue Crack Growth Threshold. [PDF]
Materials (Basel), 2023 Chapetti MD, Gubeljak N, Kozak D.
europepmc +1 more source
Growth of surface and corner cracks in beta-processed and mill-annealed Ti-6Al-4V [PDF]
Empirical stress-intensity expressions were developed to relate the growth of cracks from corner flaws to the growth of cracks from surface flaws. An experimental program using beta-processed Ti-6Al-4V verified these expressions for stress ratios, R ...
Bell, P. D.
core +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi +2 more
wiley +1 more source
Fatigue crack growth of glass fiber laminates polymer composites using vacuum bagging technique. [PDF]
PLoS OneChaloob MK +3 more
europepmc +1 more source
Stress-wave analysis technique study on thick-walled type A302B steel pressure vessels, July 1968 - July 1969 [PDF]
Stress wave analysis and crack opening displacement to monitor subcritical crack growth for grade B alloy steel pressure ...
Climent, F. J. +3 more
core +1 more source
Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina +11 more
wiley +1 more source