Results 171 to 180 of about 42,379 (316)

Continuous-discontinuous coupling model for crack initiation and propagation analysis

open access: yes, 2013
The analysis of crack initiation and propagation is essential for predicting the service life of engineering structure.A continuous-discontinuous coupling model is proposed and applied to simulate the progressing cracking problems.In continuous ...
Li SH(李世海), Wang J(王杰)
core  

Small RNA pathways in mammalian oocytes

open access: yesFEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

open access: yesFEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard   +12 more
wiley   +1 more source

Developments in advanced high temperature disc and blade materials for aero-engine gas turbine applications

open access: yes, 2012
The research carried out as part of this EngD is aimed at understanding the high temperature materials used in modern gas turbine applications and providing QinetiQ with the information required to assess component performance in new propulsion systems ...
Everitt, S., Everitt, Stewart
core  

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

open access: yesFEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya   +2 more
wiley   +1 more source

Cohesive zone models in history dependent materials

open access: yes, 2013
Copyright @ 2013 ACMECohesive zone model is a well known concept in nonlinear fracture mechanics of elasto-plastic materials. In contrast to that, we discuss a development of the cohesive zone model to linear, but time and history dependent, materials ...
Mikhailov, SE, Hakim, L
core  

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