Results 41 to 50 of about 34,504 (250)

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

An inverse method for evaluating weld residual stresses via fatigue crack growth test data [PDF]

open access: yes, 2010
This paper presents an inverse method for calculating the thermal residual stresses in welded specimens via measured fatigue crack growth rates. Firstly, fracture-mechanics superposition law has been used to extract the stress intensity factor due to ...
Rui Bao   +3 more
core   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Crack Propagation by Finite Element Method [PDF]

open access: yesFracture and Structural Integrity, 2018
Crack propagation simulation began with the development of the finite element method; the analyses were conducted to obtain a basic understanding of the crack growth.
Luiz Carlos H. Ricardo
doaj   +1 more source

Dynamic crack propagation characteristics of CNG tanks during physical explosion

open access: yesYou-qi chuyun, 2022
CNG tanks have the potential risk of physical explosion. In order to study the dynamic crack propagation characteristics of CNG tanks during physical explosion, a numerical analysis model of fluid-solid coupling was established based on the thermo ...
Lifeng LI   +4 more
doaj   +1 more source

Corrosion Fatigue Crack Propagation Behaviour of a High Strength Low Alloy Steel in a Synthetic Sea Water Environment. [PDF]

open access: yes, 1986
The corrosion fatigue crack propagation behaviour of a high strength low alloy steel, N-A-XTRA 70, in a synthetic sea water solution was tested using S. E. N. specimens subjected to a loading frequency of 0.1 Hz and a load ratio of 0.6.
Millar, Peter G.
core  

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

Analysis of Crack Propagation in Micro-solder bumps

open access: yesJOURNAL OF THE JAPAN WELDING SOCIETY, 2010
In the electronics equipment field, dominated by information and communications and motor vehicles, solder, with its excellent ductility, is used to connect LSI and other electronic parts to circui...
openaire   +2 more sources

Finite element analysis of bonded crack retarders for integral aircraft structures [PDF]

open access: yes, 2009
Trends in aircraft design and manufacture are towards the reduction of manufacturing cost and structural weight while maintaining high level of safety. These reductions can be achieved by using integral structures.
Boscolo, Marco
core  

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

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