Results 21 to 30 of about 2,962 (211)
This paper provides further understanding of the peak load effect on micro-crack formation and residual stress relaxation. Comprehensive numerical simulations using the finite element method are applied to simultaneously take into account the effect of ...
Jairan Nafar Dastgerdi +3 more
doaj +1 more source
Fracture Mechanical Behavior of Cracked Cantilever Roof with Large Cutting Height Mining
Accurately predicting the roof collapse span is crucial in ensuring the safe production of thick seam mining with large mining height, which is easy in forming a “cantilever beam” structure.
Zenghui Zhao +4 more
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Resonant Scattering and Crack Sizing
Theoretical consideration of ultrasonic scattering from interior cracks has received considerable attention in recent years. These studies have led to scattering amplitude computations for ultrasonic backscatter from circular cracks by the method of optimal truncation (MOOT) (1, 2) and by T-matrix techniques (3).
Gray, Timothy, Rose, J.
openaire +3 more sources
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Influence of different sizes of concrete and roller compacted concrete on double-K fracture parameters [PDF]
Affected by physical properties of various components, characteristics and stress states of junction surface and other multiple factors, concrete, as a kind of multi-phase composite material, has complicated failure mechanism, thus making its fracture ...
Liu Chunjiang, Zhang Huabo, Lv Ninghua
doaj +1 more source

