Results 191 to 200 of about 12,878 (286)

Investigating transthyretin variants H88R and I107V in amyloid priming: From destabilization to complete dissociation

The FEBS Journal, EarlyView.
Investigated mutations in transthyretin (TTR) disrupt the F87‐centered hydrophobic core that stabilizes its tetrameric structure. The mild I107V mutation weakens inter‐chain packing, while H88R fully abolishes tetramer formation, yielding a monomeric, aggregation‐prone form. Structural, biophysical, and computational analyses reveal that both mutations
István L. Bódy, Zsolt Fazekas, Nóra Wágner, Anna J. Kiss‐Szemán, Veronika Harmat, Zoltán Pozsonyi, Dóra K. Menyhárd, András Perczel   +7 more
wiley   +1 more source

Biomechanical analysis of anatomical intramedullary nails and proximal femoral anti-rotation-II intramedullary nails for the treatment of unstable intertrochanteric fractures (AO type 31-A2.2) in older patients. [PDF]

J Orthop Surg Res
Ma XW, Chen J, Hu Y, Fan ZR.
europepmc   +1 more source

Bio‐active designed peptide for hair keratin strengthening

International Journal of Cosmetic Science, EarlyView.
Bioactive tripeptides through in silico screening revealed KCV (Tripeptide‐132) as the most promising keratin‐targeting candidate. Experimental studies confirmed its superior hair‐strengthening performance with 44% tensile strength enhancement, 50% breakage reduction, improved surface integrity and fibre penetration.
Chan‐Su Rha, Byeong Gyu In, Kilsun Myoung, Chaeyeon Song, Eun‐Soo Lee, Heung Soo Baek, Won Seok Park   +6 more
wiley   +1 more source

Al₂O₃/Al hybrid nanolaminates with superior toughness, strength and ductility. [PDF]

Nat Commun
Baral P, Jaddi S, Wang H, Orekhov A, Gauquelin N, Bagherpour A, Van Loock F, Coulombier M, Favache A, Rusinowicz M, Verbeeck J, Lucas S, Raskin JP, Idrissi H, Pardoen T.   +14 more
europepmc   +1 more source

Neurotrophic extracellular matrix proteins promote neuronal and iPSC astrocyte progenitor cell‐ and nano‐scale process extension for neural repair applications

Journal of Anatomy, Volume 246, Issue 4, Page 585-601, April 2025.
The extracellular matrix plays a critical role in modulating cell behaviour in the central nervous system influencing neural cell morphology and growth. However, a better understanding of the impact of individual matrix proteins on both neurons and astrocytes is critical for advancing the development of matrix‐based neural repair strategies.
Cian O'Connor, Rena E. Mullally, Sarah F. McComish, Julia O'Sullivan, Ian Woods, Ingmar Schoen, Massimiliano Garre, Maeve A. Caldwell, Adrian Dervan, Fergal J. O'Brien   +9 more
wiley   +1 more source

Evolutive phase field modelling of fracture behavior of cemented paste backfill under Mode-I loading condition. [PDF]

Sci Rep
Yang J, Fang K, Hao S, Feng G, Cui L.
europepmc   +1 more source

Inflammatory and Immunological Basis of Periodontal Diseases

Journal of Periodontal Research, EarlyView.
The periodontal lesion emerges as an evolving immunological battlefield, where host–microbiome interactions, dysregulated immune responses, fragile resolution mechanisms, and inflammophilic dysbiosis converge to shift the balance from homeostasis to unrestrained tissue destruction.
Giacomo Baima, Marion Arce, Mario Romandini, Thomas Van Dyke   +3 more
wiley   +1 more source

Interface Rotation in Accumulative Rolling Bonding (ARB) Cu/Nb Nanolaminates Under Constrained and Unconstrained Loading Conditions as Revealed by In Situ Micromechanical Testing. [PDF]

Nanomaterials (Basel)
Sahay R, Radchenko I, Ananthasubramanian P, Harito C, Briffod F, Yasuda K, Shiraiwa T, Jhon M, Speaks R, Speaks D, Lee K, Enoki M, Raghavan N, Budiman AS.   +13 more
europepmc   +1 more source

Comprehensive and Comparative Transcriptional Profiling of the Cell Wall Stress Response in Bacillus subtilis

Molecular Microbiology, EarlyView.
Transcriptional profiling of the primary cell envelope stress response (CESR) of Bacillus subtilis exposed to a range of cell wall‐targeting antimicrobials, combining RNAseq and high‐resolution tiling arrays. We revealed the complexity of the CESR, the contribution of extracytoplasmic function sigma factors (ECFs) and two‐component signal transduction ...
Qian Zhang, Charlène Cornilleau, Lena Friebel, Sarah Spitzner, Raphael R. Müller, Doreen Meier, Pierre Flores, Cyprien Guérin, Pierre Nicolas, Diana Wolf, Vincent Fromion, Rut Carballido‐López, Thorsten Mascher   +12 more
wiley   +1 more source

Self-Healing Polymer Nanocomposites: Mechanisms, Structure-Property Relationships, and Emerging Applications. [PDF]

Polymers (Basel)
Sharma SK, Gajević S, Sharma LK, Sharma Y, Sharma M, Ivanović L, Milojević S, Stojanović B.   +7 more
europepmc   +1 more source