Results 1 to 10 of about 37,752 (261)

Smart polymers for the controlled delivery of drugs – a concise overview [PDF]

Acta Pharmaceutica Sinica B, 2014
Smart polymers have enormous potential in various applications. In particular, smart polymeric drug delivery systems have been explored as “intelligent” delivery systems able to release, at the appropriate time and site of action, entrapped drugs in ...
Honey Priya James, Rijo John, Anju Alex, Anoop K.R.   +3 more
doaj   +4 more sources

Smart polymers for cell therapy and precision medicine [PDF]

Journal of Biomedical Science, 2019
Soft materials have been developed very rapidly in the biomedical field over the past 10 years because of advances in medical devices, cell therapy, and 3D printing for precision medicine. Smart polymers are one category of soft materials that respond to
Hung-Jin Huang, Yu-Liang Tsai, Shih-Ho Lin, Shan-hui Hsu   +3 more
doaj   +2 more sources

Electroactive Smart Polymers for Biomedical Applications [PDF]

Materials, 2019
Humberto Palza, Carolina Angulo-Pineda, Paula A Zapata   +2 more
exaly   +2 more sources

Dendronized Gelatin-Mediated Synthesis of Gold Nanoparticles

Molecules, 2022
Thermoresponsive dendronized gelatins (GelG1) or gelatin methacrylates (GelG1MA) were used as precursors to modulate the efficient reduction of Au(III) to form stable gold nanoparticles (AuNPs) through UV irradiation.
Yan Ding, Xiacong Zhang, Wen Li, Afang Zhang   +3 more
doaj   +1 more source

Dual-Responsive Supramolecular Chiral Assemblies from Amphiphilic Dendronized Tetraphenylethylenes

Molecules, 2023
Supramolecular assembly of amphiphilic molecules in aqueous solutions to form stimuli-responsive entities is attractive for developing intelligent supramolecular materials for bioapplications.
Jianan Zhang, Xueting Lu, Wen Li, Afang Zhang   +3 more
doaj   +1 more source

A rationally designed cancer vaccine based on NIR-II fluorescence image-guided light-triggered remote control of antigen cross-presentation and autophagy

Acta Pharmaceutica Sinica B, 2023
Cancer vaccines represent a promising immunotherapeutic treatment modality. The promotion of cross-presentation of extracellular tumor-associated antigens on the major histocompatibility complex (MHC) class I molecules and dendritic cell maturation at ...
Aihua Wu, Afeng Yang, Qinli Tong, Guoguang Wei, Sihang Zhang, Sheng Yu, Chen Zhang, Jiaojiao Xu, Wei Lu   +8 more
doaj   +1 more source

Pheophorbide A–Mediated Photodynamic Therapy Potentiates Checkpoint Blockade Therapy of Tumor with Low PD–L1 Expression

Pharmaceutics, 2022
Although the immune checkpoint blockade (ICB) has made a great success in cancer immunotherapy, the overall response rate to the ICB, such as anti–programmed death ligand 1 (PD–L1) therapy, remains only at 20–30%.
Qinli Tong, Jiaojiao Xu, Aihua Wu, Chen Zhang, Afeng Yang, Sihang Zhang, Hongzheng Lin, Wei Lu   +7 more
doaj   +1 more source

Intravital Microscopy Reveals Endothelial Transcytosis Contributing to Significant Tumor Accumulation of Albumin Nanoparticles

Pharmaceutics, 2023
The principle of enhanced permeability and retention (EPR) effect has been used to design anti-cancer nanomedicines over decades. However, it is being challenged due to the poor clinical outcome of nanoparticles and controversial physiological foundation.
Guoguang Wei, Sihang Zhang, Sheng Yu, Wei Lu   +3 more
doaj   +1 more source

Small interfering RNA delivery to the neurons near the amyloid plaques for improved treatment of Alzheimer׳s disease

Acta Pharmaceutica Sinica B, 2019
Gene therapy represents a promising treatment for the Alzheimer׳s disease (AD). However, gene delivery specific to brain lesions through systemic administration remains big challenge.
Qian Guo, Xiaoyao Zheng, Peng Yang, Xiaoying Pang, Kang Qian, Pengzhen Wang, Shuting Xu, Dongyu Sheng, Liuchang Wang, Jinxu Cao, Wei Lu, Qizhi Zhang, Xinguo Jiang   +12 more
doaj   +1 more source

Cellulose nanocrystals in smart and stimuli-responsive materials: a review

Materials Today Advances, 2020
“Smart” stimuli-responsive materials have been the subject of decades of research because of their versatility and particularly their use in medical and sensing applications.
R. Nasseri, C.P. Deutschman, L. Han, M.A. Pope, K.C. Tam   +4 more
doaj   +1 more source