Results 41 to 50 of about 3,855,615 (290)

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model

open access: yesFEBS Open Bio, EarlyView.
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito   +7 more
wiley   +1 more source

Investigation of Desiccation Cracking Behavior of Waste Carbon Fiber–Reinforced Clay Material

open access: yesBuildings
Carbon fiber is a common waste building material, but its effect on the drying and cracking properties of clay materials is unknown. In this paper, crack rate and fractal dimension are used to characterize the influence of waste carbon fiber materials on
Fei Chen   +4 more
doaj   +1 more source

Desiccation Cracking Behavior of MICP-Treated Bentonite

open access: yesGeosciences, 2019
This study aims to characterize the effect of microbial-induced calcite precipitation (MICP) on the desiccation cracking behaviors of compacted calcium bentonite soils.
Mark Vail   +5 more
doaj   +1 more source

In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols

open access: yesFEBS Open Bio, EarlyView.
Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton   +6 more
wiley   +1 more source

Failure characteristics and the energy criterion of rock with a through‐going joint under true‐triaxial unloading conditions: Insights from the DEM model

open access: yesDeep Underground Science and Engineering
Excavation unloading damages rock masses, with preferential failure along geological defects in rock engineering, which may induce catastrophe geological hazards.
Fei Liu   +4 more
doaj   +1 more source

Effect of Local Strain Distribution of Cold-Rolled Alloy 690 on Primary Water Stress Corrosion Crack Growth Behavior

open access: yesArchives of Metallurgy and Materials, 2017
This work aims to study the stress corrosion crack growth behavior of cold-rolled Alloy 690 in the primary water of a pressurized water reactor. Compared with Alloy 600, which shows typical intergranular cracking along high angle grain boundaries, the ...
Kim S.-W.   +3 more
doaj   +1 more source

Heterotropic regulation and negative homotropic cooperativity

open access: yesFEBS Open Bio, EarlyView.
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea   +5 more
wiley   +1 more source

Hydrogen distribution and redistribution in the weld zone of constructional steels [PDF]

open access: yes, 1999
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.The invention of electric arc welding revolutionized the steel construction industry, but also brought some problems when the welded region has inferior ...
Smith, Richard Dominic
core   +6 more sources

Influência das fibras de aço e das adições minerais na fissuração de tirantes de concreto armado

open access: yesRevista IBRACON de Estruturas e Materiais
Neste trabalho é investigada a influência das fibras de aço e das adições minerais (sílica ativa e cinza volante) na fissuração de tirantes de concreto armado.
L. A. Oliveira Júnior   +4 more
doaj   +1 more source

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