Results 121 to 130 of about 108,978 (268)
Investigating the Thermal Cracking Processes of a Concrete Disk Considering the Influences of Aggregates and Pores: A Numerical Study Based on DEM. [PDF]
Hu S, Zhu X, Shi J, Li Y, Yu S.
europepmc +1 more source
Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana +5 more
wiley +1 more source
Mechanical Behavior and Failure Modes of Cemented Backfill Under Impact Loading. [PDF]
Zhang X +6 more
europepmc +1 more source
Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan +11 more
wiley +1 more source
MCGC-Net: A Text-Enhanced Geometry-Consistent Network for UAV-Based Road Crack Detection. [PDF]
Ou Z, He S, Bu R, Wang P, Gong G.
europepmc +1 more source
We report the first β‐glucosidase with demonstrated hydrolytic activity on an N‐linked glycopyranoside. The enzyme, native to maize, was biochemically characterised for this novel reaction, and structural modelling of the enzyme–substrate complex revealed several clues to the underlying reduced catalytic rate relative to its native O‐glycopyranoside ...
Hani Gharabli +3 more
wiley +1 more source
Moisture-driven local strain development in ASR-damaged concrete. [PDF]
Azad S, Trtik P, Strobl M, Kaestner A.
europepmc +1 more source
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty +13 more
wiley +1 more source
Shield Tunnel Crack Detection Based on Improved Unet. [PDF]
Ming G, Ye XW, Hang D, Qin JS, Li J.
europepmc +1 more source

