Results 41 to 50 of about 108,978 (268)
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Torsional Behavior of Pylon Columns with Edge Cracks in Suspension Bridges Under Wind Loads
BuildingsCracks inevitably develop in the pylon structures of suspension bridges due to external forces such as wind loads. Cracks are a primary cause of torsional damage to the key supporting structures of suspension bridges.
Nan Liu +7 more
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
, 2007 Database indices provide a non-discriminative navigational infrastructure to localize tuples of interest. Their maintenance cost is taken during database updates. In this paper, we study the complementary approach, addressing index maintenance as part of query processing using continuous physical reorganization, i.e., cracking the database into ...
S. Idreos (Stratos) +2 more
openaire +2 more sources
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Effect of Reinforced Concrete Cracking on Chloride Ion Penetration
MATEC Web of Conferences, 2015 This article is to explore the effect of conditions of reinforced concrete on chloride ion penetration. The influence of the crack width and the thickness of protective layer were studied.
Yuan Chao, Li Yang, Chen Xu, Wang Wenjie
doaj +1 more source
Detection and Evaluation of Construction Cracks through Image Analysis Using Computer Vision
Applied Sciences, 2023 The introduction of artificial intelligence methods and techniques in the construction industry has fostered innovation and constant improvement in the automation of monitoring and control processes at construction sites, although there are areas where ...
Alexandre Almeida Del Savio +4 more
doaj +1 more source
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Deep Learning-Driven Design and Analysis of an Autonomous Robotic System for In-Pipe Inspection
AlgorithmsThis paper presents an intelligent robotic system for in-pipe inspection that integrates a novel mechanical design, deep learning-based defect detection, and high-fidelity simulation for real-time validation.
Ambigai Rajasekaran +9 more
doaj +1 more source