Results 51 to 60 of about 196,226 (299)

About Craft Production on the Bulgar Settlements of the XI – Beginning of the XIII Century

open access: yesАрхеология евразийских степей, 2022
The article deals with issues related to the study of crafts on the unfortified settlements of Volga Bulgaria. In the first study on this topic Ye.P. Kazakov suggested that on the settlements located in the Lower Kama areas in the second half of the 10th
Rudenko Konstantin A.
doaj   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

open access: yesMolecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Craft in unexpected places [PDF]

open access: yes, 2012
Within the shifting territories of craft practice, the handmade has become a relational form of contemporary activity that transforms our understanding of place through a hands-on, minds-on process of collective-making.
Barber, C.   +8 more
core   +1 more source

Silicon fertilizer increased potato drought tolerance and reduced soil N2O emissions in two Danish soils at field scale

open access: yesScientific Reports
Silicon (Si) fertilization enhances drought tolerance, but its effectiveness under field conditions and drought intensities remains uncertain. Moreover, the role of Si in regulating greenhouse gas emissions is poorly understood. Therefore, we conducted a
Yvonne Musavi Madegwa   +3 more
doaj   +1 more source

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

The Milord Carriage from Brijuni, History and Conservation / Brijunska kočija tipa milord, povijest i konzervacija

open access: yesMiscellanea Hadriatica et Mediterranea, 2015
The Milord (Mylord) carriage in possession of the National Park Brijuni is a forerunner of the Victoria carriage. Owing to their similar characteristics, they can easily be mixed up.
Sonja Kirchhoffer , Zoran Kirchhoffer
doaj   +1 more source

NAPRT loss promotes lung tumor initiation and growth through AKT signaling independently of NAD+ biosynthesis

open access: yesMolecular Oncology, EarlyView.
Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh   +11 more
wiley   +1 more source

Reflections on a craft design protocol [PDF]

open access: yes, 2011
For some years I have been working on a design protocol of craft, which aims to unearth the working principles of one cultural area (contemporary craft) of production for the benefit of another (interaction design).
Kettley, S
core  

The craft process developing student decision making

open access: yesTechne Series: Research in Sloyd Education and Craft Science A, 2016
In enterprise education, learning is problem-focused and holistic. A learning process that encourages people to learn by doing develops their problem-solving skills, participation, interaction, and decision making.
Marja-Leena Rönkkö, Jaana Lepistö
doaj  

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