Results 71 to 80 of about 873,986 (280)

What is intrinsic motivation? A typology of computational approaches

open access: yesFrontiers in Neurorobotics, 2009
Intrinsic motivation, the causal mechanism for spontaneous exploration and curiosity, is a central concept in developmental psychology. It has been argued to be a crucial mechanism for open-ended cognitive development in humans, and as such has gathered ...
Pierre-Yves Oudeyer, Frederic Kaplan
doaj   +1 more source

Understanding bio‐based polymers: A study of origins, properties, biodegradation and their impact on health and the environment

open access: yesFEBS Open Bio, EarlyView.
This review provides an overview of bio‐based polymer sources, their unique functional properties and their environmental impact, and addresses their role as sustainable alternatives. It discusses end‐of‐life options, including composting and anaerobic digestion for renewable energy.
Sabina Kolbl Repinc   +8 more
wiley   +1 more source

Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes

open access: yesFEBS Open Bio, EarlyView.
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde   +3 more
wiley   +1 more source

THE PACIFIC FLEET AS A FACTOR IN THE SECURITY OF RUSSIA AT THE END OF THE XIX AND THE BEGINNING OF THE XX CENTURIES

open access: yesГуманитарные и юридические исследования, 2021
The formation of a new geopolitical system in modern political, socio-economic and geographical conditions draws us to the experience of the past, when in the conditions of military-political conflicts of the late XIX - early XX century the formation of ...
A. Zubow, T. Sidnenko
doaj  

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

open access: yesFEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn   +4 more
wiley   +1 more source

Deep Learning–Assisted Differentiation of Four Peripheral Neuropathies Using Corneal Confocal Microscopy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Peripheral neuropathies contribute to patient disability but may be diagnosed late or missed altogether due to late referral, limitation of current diagnostic methods and lack of specialized testing facilities. To address this clinical gap, we developed NeuropathAI, an interpretable deep learning–based multiclass classification ...
Chaima Ben Rabah   +7 more
wiley   +1 more source

Designing for tacit learning: an investigation of design strategies for multimedia supported learning in the crafts [PDF]

open access: yes, 2003
There is an increasing interest and activity in the design of interactive multimedia to support learning in all fields of education and training. However, most of the theory to support such developments is concerned with learning explicit knowledge and ...
Rust, C., Wood, N.
core  

Multicriteria VMAT optimization

open access: yes, 2011
Purpose: To make the planning of volumetric modulated arc therapy (VMAT) faster and to explore the tradeoffs between planning objectives and delivery efficiency. Methods: A convex multicriteria dose optimization problem is solved for an angular grid of
Bedford   +37 more
core   +1 more source

Prediction of Myasthenia Gravis Worsening: A Machine Learning Algorithm Using Wearables and Patient‐Reported Measures

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Myasthenia gravis (MG) is a rare disorder characterized by fluctuating muscle weakness with potential life‐threatening crises. Timely interventions may be delayed by limited access to care and fragmented documentation. Our objective was to develop predictive algorithms for MG deterioration using multimodal telemedicine data ...
Maike Stein   +7 more
wiley   +1 more source

LACANIAN UNCONSIOUS IN DYLAN THOMAS \"ELEGY\" AND \"IN MY CRAFT OR SULLEN ART\" [PDF]

open access: yes, 2012
LACANIAN UNCONSIOUS IN DYLAN THOMAS \"ELEGY\" AND \"IN MY CRAFT OR SULLEN ART\" - Psychoanalysis, Unconscious, Dylan Thomas, Metaphor ...
KRISTIANTI, YOAN, Retnowati, Retnowati
core  

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