Results 21 to 30 of about 16,669 (267)

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Influence of Leaf Area Index and Plant Height on Green Roof Carbon Footprint in Moroccan Residential Buildings in Hot Climates [PDF]

EPJ Web of Conferences
Green roofs are a sustainable solution to reduce energy consumption and carbon footprints, especially in hot climates. This study investigates the influence of two key design parameters, Leaf Area Index (LAI) and plant height, on the thermal performance ...
Idouanaou Abdessamad, Malha Mustapha, Bah Abdellah, Kardellass Saïd   +3 more
doaj   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Impact of Shading and Glazing Types of Trombe Walls on the Carbon Footprint of Residential Buildings in Morocco [PDF]

E3S Web of Conferences
This paper investigates the impact of shading and glazing types on the performance of Trombe walls in reducing the carbon footprint of Moroccan residential buildings.
Idouanaou Abdessamad, Cherqi Oumayma, Malha Mustapha, Bah Abdellah   +3 more
doaj   +1 more source

COMPREHENSIVE MACHINE LEARNING AND DEEP LEARNING APPROACHES FOR PARKINSON'S DISEASE CLASSIFICATION AND SEVERITY ASSESSMENT

Informatyka, Automatyka, Pomiary w Gospodarce i Ochronie Środowiska, 2023
In this study, we aimed to adopt a comprehensive approach to categorize and assess the severity of Parkinson's disease by leveraging techniques from both machine learning and deep learning.
Oumaima Majdoubi, Achraf Benba, Ahmed Hammouch   +2 more
doaj   +1 more source

Friedel–Crafts Polymerizations [PDF]

Nature, 1946
α-METHYLSTYRENE has been polymerized at 25° C., using stannic chloride as catalyst, both in solution and in undiluted monomer, giving polymers of molecular weight up to approximately 11,000. Staudinger1, using this catalyst, obtained only a very low degree of polymerization (up to octamer), presumably due to the high temperatures reached in his ...
openaire   +2 more sources

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Application of Huangling mianhua image recognition and classification system based on deep learning

Discover Computing
Traditional methods for recognizing Huangling mianhua images suffer from poor generalization, insufficient local-detail perception and weak robustness, because they still rely on hand-crafted features or standard convolutional neural networks.
Dazhuang Li, Lei Gao, Xiaolong Lai, Zhengkang Ou, Jingzhen Yan, Chaolong Wu   +5 more
doaj   +1 more source

Comprehensive Analysis and Future Prospects of Electric Vehicles: Topologies, Efficiency, Challenges, and Power Integration [PDF]

EPJ Web of Conferences
The electrification of transportation has received considerable attention in modern society for achieving sustainable energy targets. But electric vehicle sales still account for a small proportion in transportation sector.
Bounagui Mohamed, Nasser Tamou, Essadki Ahmed, Akarne Youssef   +3 more
doaj   +1 more source