Results 91 to 100 of about 543,139 (298)

Metabolic Reprogramming in Glioblastoma Stem Cells Promotes Radiation Resistance Through a H3K18la/USP30/MBOAT2 Axis

open access: yesAdvanced Science, EarlyView.
LDHA‐driven lactate production in mesenchymal glioma stem cells promotes p300‐dependent H3K18 lactylation, activates USP30 transcription, and stabilizes MBOAT2 to remodel phosphatidylethanolamines toward ferroptosis‐resistant PE‐MUFA species. Disrupting this metabolic–epigenetic–lipid circuit enhances ferroptosis and sensitizes glioblastoma to ...
Zong Miao   +13 more
wiley   +1 more source

Pupil-sparing third cranial nerve palsy with aberrant regeneration secondary to cavernous sinus arachnoid cyst

open access: yeseNeurologicalSci, 2019
A 66 year-old woman presented with a pupil-sparing partial third cranial nerve palsy with aberrant regeneration. Imaging revealed a cystic lesion in the right cavernous sinus, demonstrating signal characteristics consistent with arachnoid cyst ...
Kelly A. Malloy   +2 more
doaj   +1 more source

Cranial Nerve Three Palsy

open access: yes, 2019
Dr.
Andrew G. Lee, MD; Peter Ugoh
core  

Extracellular CIRP Dysregulates Microglial Efferocytosis in Acute Ischemic Stroke via the TLR4/miR‐155/MafB Axis

open access: yesAdvanced Science, EarlyView.
eCIRP released in the stroke brain binds to TLR4 expressed on microglia to induce miR‐155, which suppresses MafB, decreases MerTK and downstream signaling to impair efferocytosis of apoptotic neurons, worsening the acute stroke outcomes. Inhibition of eCIRP‐TLR4 interaction with small peptide C23 attenuates eCIRP‐induced microglial efferocytic ...
Dmitriy Lapin   +3 more
wiley   +1 more source

Cranial neurolymphomatosis and its oncologic counterparts: Case series on malignant cranial nerve neuropathies

open access: yesSAGE Open Medical Case Reports
Neurolymphomatosis occurs due to the infiltration of a nerve by malignant cells. Cranial neurolymphomatosis is a rare disease process associated with non-solid tumors (i.e., lymphoma, leukemia, etc.).
Bahadar S Srichawla   +2 more
doaj   +1 more source

Ocular cranial nerve palsies secondary to sphenoid sinusitis

open access: yesWorld Journal of Otorhinolaryngology-Head and Neck Surgery, 2017
Objective: The clinical presentation of sphenoid sinusitis can be highly variable. Rarely, sphenoid sinusitis may present with cranial nerve complications due to the proximity of these structures to the sphenoid sinus.
Aiman El Mograbi, Ethan Soudry
doaj   +1 more source

Engineered Brain‐Targeted Exosomes Delivering FGF1 for Sustained Glycemic Regulation and Multitarget Neurovascular Protection in Diabetic Stroke

open access: yesAdvanced Science, EarlyView.
ABSTRACT Diabetic stroke is characterized by a hyperglycemic and pro‐inflammatory microenvironment that exacerbates neurovascular dysfunction. However, the blood–brain barrier (BBB) remains a formidable obstacle, restricting the delivery of most therapeutic molecules.
Bixin Shen   +7 more
wiley   +1 more source

Analysis and methods of prevention of cranial nerves injury during carotid endarterectomy

open access: yesИнновационная медицина Кубани, 2019
Aim. CEAE is an effective method of ischemic stroke prevention. However, as any invasive treatment method, CEAE is associated with a risk of complications in the early and late postoperative periods.
A. V. Matyushkin, A. Kh. Mustafin
doaj   +1 more source

Cranial Nerve Six Palsy

open access: yes, 2019
Dr.
Andrew G. Lee, MD; Asad Loya
core  

Disorders of the Fourth Cranial Nerve

open access: yes, 2021
This review of disorders of the fourth cranial nerve includes discussion on anatomy, examination techniques, congenital and acquired etiologies, differential diagnosis, and management options. The findings of the superior oblique muscle on orbital MRI in
Lanning B. Kline; Joseph L. Demer; Michael S. Vaphiades; Mehdi Tavakoli
core  

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