Results 161 to 170 of about 215,002 (330)

The Evolving Landscape of Immunotoxicity: Charting Mechanisms and Future Strategies for Immune Checkpoint Inhibitor Adverse Events

open access: yesMed Research, EarlyView.
ABSTRACT The use of immune checkpoint inhibitors (ICIs) has significantly improved the efficacy of cancer therapy, but their associated immune‐related adverse events (irAEs) can severely compromise treatment safety. This review systematically summarizes the core mechanisms underlying irAEs, which include multi‐organ damage resulting from T‐cell ...
Anqi Lin   +8 more
wiley   +1 more source

Diffuse cranial nerve infiltration in acute lymphoblastic leukemia: MRI diagnosis. [PDF]

open access: yesRadiol Case Rep
Ali M   +7 more
europepmc   +1 more source

Early Levodopa Therapy in Tyrosine Hydroxylase Deficiency

open access: yes
Movement Disorders Clinical Practice, EarlyView.
Claudio M. de Gusmao   +4 more
wiley   +1 more source

A Novel α‐Synuclein K58N Missense Variant in a Patient with Parkinson's Disease

open access: yesMovement Disorders, EarlyView.
Abstract Background Parkinson's disease (PD) is a complex multifactorial disorder with a genetic component in about 15% of cases. Multiplications and point mutations in SNCA gene, encoding α‐synuclein (aSyn), are linked to rare familial forms of PD. Objective Our goal was to assess the clinical presentation and the biological effects of a novel K58N ...
Mohammed Al‐Azzani   +24 more
wiley   +1 more source

Vagus Nerve Stimulation in Movement Disorders, from Principles to a Systematic Review of Evidence

open access: yesMovement Disorders, EarlyView.
Abstract Background The vagus nerve (VN), the principal component of the parasympathetic branch of the autonomic nervous system (ANS), mediates bidirec communication between the central nervous system (CNS) and peripheral organs. Vagus nerve stimulation (VNS), delivered through invasive (iVNS) or non‐invasive (transcutaneous cervical [tcVNS] and ...
Francesca Proietti   +9 more
wiley   +1 more source

Novel Biallelic SQSTM1 Mutation Causing a Subacute‐Onset Complex Movement Disorder with Oculomotor Abnormalities

open access: yes
Movement Disorders Clinical Practice, EarlyView.
Ana Luísa de Almeida Marcelino   +8 more
wiley   +1 more source

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