Results 31 to 40 of about 7,489 (221)

Craniocerebral and Spinal Trauma

, 2020
Pediatric head injury is common in our environment and occurs mostly due to fall from heights, but motor vehicle accidents cause the severest form of injury. Child abuse is increasingly becoming recognized as a cause of pediatric head injury. Management is multidisciplinary. Prompt resuscitation and cervical spine protection are key to survival.
BB Shehu, Muhammad Raji Mahmud
openaire   +2 more sources

[Craniocerebral trauma in childhood].

Der Radiologe, 2004
This article describes typical head injuries in infants and children. In comparison with adults there are distinct differences in the etiology of trauma and in the kind of reaction of the skull and brain. In infants and children there are three different types of trauma: birth trauma, accidental and non-accidental injury.
Struffert, T, Grunwald, I, Reith, W
openaire   +2 more sources

Regulating PPARG Reduces Lipid Accumulation in Microglia and Promotes Functional Recovery After Spinal Cord Injury

Advanced Science, EarlyView.
Macrophages infiltrate the spinal cord post‐injury, decreasing over time. Microglia phagocytose myelin debris, increasing lipid accumulation. Macrophage deletion improves outcomes, while microglial deletion worsens them. The LD+ microglia subtype shows abnormal Pparg signaling.
Mingran Luo, Jiayun Liu, Yunxin Su, Tao Jiang, Xincan Wu, Peng Gao, Tao Qin, Mengyuan Wu, Qingqing Li, Shujun Zhang, Baorong He, Yongxiang Wang, Xiaodong Guo, Wei Zhou, Shujie Zhao, Jin Fan, Jian Chen, Guoyong Yin   +17 more
wiley   +1 more source

Study on cumulative effects of biological craniocerebral trauma under repeated blast

Theoretical and Applied Mechanics Letters
Repeated blast impacts on personnel in explosive environments can exacerbate craniocerebral trauma. Most existing studies focus on the injury effects of a single blast, lacking in-depth analysis on the injury effects and cumulative effects of repeated ...
Xingyuan Huang, Bingchen Xia, Lijun Chang, Zhikang Liao, Hui Zhao, Zhihua Cai   +5 more
doaj   +1 more source

Advanced Image‐Guidance and Surgical‐Navigation Techniques for Real‐Time Visualized Surgery

Advanced Science, EarlyView.
This review comprehensively summarizes advances in surgical navigation, covering both established and emerging intraoperative imaging technologies. It highlights mechanisms, advantages, limitations, and clinical applications, while emphasizing interdisciplinary collaboration.
Xiaoxiao Fan, Xiaolong Liu, Qiming Xia, Guoqiao Chen, Jiaxi Cheng, Zhaoqi Shi, Yifeng Fang, Parikshit Asutosh Khadaroo, Jun Qian, Hui Lin   +9 more
wiley   +1 more source

CLINICAL PICTURE, MODERN APPROACHES IN DIAGNOSTICS OF TRAUMATIC INTRACRANIAL HEMATOMAS

Вестник хирургии имени И.И. Грекова, 2018
An analysis of 93 patients with traumatic intracranial hematomas of different degree of severity of craniocerebral trauma was made. The patients consist of 59 (63,4%) boys and 36 (36,6%) girls. In most cases, the cause of craniocerebral injury was a fall
Sh. A. Turdiboev, R. N. Berdiev, Kh. D. Rakhmonov, Kh. A. Giyosov   +3 more
doaj   +1 more source

Safety, Pharmacokinetics, and Pharmacodynamics of Osivelotor for Sickle Cell Disease: First‐in‐Human Studies in Healthy Participants and Patients

Clinical Pharmacology &Therapeutics, EarlyView.
The investigational agent osivelotor, a small molecule hemoglobin (Hb) modifier in development for the treatment of sickle cell disease (SCD), acts by increasing Hb‐oxygen affinity and inhibiting the polymerization of sickle Hb. We report safety, pharmacokinetic (PK), and pharmacodynamic (PD) data from the first two phase 1 clinical trials of ...
Eleanor A. Lisbon, R. Clark Brown, Andrew Redfern, Ken Duchin, Aline Barth, Erika S. Roberts, Polo Gaputan, Kobina Dufu, Arthur Lo, Mira Patel Pochron, David R. Archer, Wai Chin, Karena Kong, Carla B. Washington, Adeyemi Adenola, Eric I. Zimmerman   +15 more
wiley   +1 more source

A Study on the Addictive Feature of Nonsuicidal Self‐Injury in Adolescents With Depression Disorders and Its Correlation With Serum Beta‐Endorphin Concentration and Neural Reward Responsiveness

iRADIOLOGY, EarlyView.
NSSI is addictive in adolescents with depression disorders. It may be related to the decrease of serum beta‐endorphin concentration and the activation of brain reward system. ABSTRACT Background Nonsuicidal self‐injury (NSSI) in adolescents with depression disorders often exhibits addictive patterns, potentially linked to serum beta‐endorphin levels ...
Jie Li, Xiaogang Zhu, Peiwen Zhang, Yuxing Wang, Jian Zhong, Yiming Wang, Lixia Yang   +6 more
wiley   +1 more source

Epidemiology and structure concomitant craniocerebral and skeletal injuries in Tashkent

Бюллетень сибирской медицины, 2008
In period of 2001—2004 in Tashkent we observe growing concomitant craniocerebral and skeletal injuries (CCCSI) on 4,8% per annum. People of working age (at the age of 21—60) often get concomitant craniocerebral and skeletal injuries (CCCSI) though males ...
A. A. Turapov, S. S. Rabinovich, K. E. Makhkamov, M. E. Burnashev, E. Yu. Valiyev, T. S. Musayev   +5 more
doaj   +1 more source

Serious outcomes among emergency department patients with presyncope: A systematic review

Academic Emergency Medicine, EarlyView.
Abstract Background Syncope is transient loss of consciousness, and in presyncope, patients experience same prodromal symptoms without losing consciousness. While studies have extensively reported the risk of serious outcome among emergency department (ED) syncope, the outcome for patients with presyncope and their management are not well studied.
Hadi Mirfazaelian, Ian Stiell, Rasoul Masoomi, Khazar Garjani, Venkatesh Thiruganasambandamoorthy   +4 more
wiley   +1 more source