Results 1 to 10 of about 76,690 (303)
Dynamic enhancer landscapes in human craniofacial development [PDF]
Nature CommunicationsThe genetic basis of human facial variation and craniofacial birth defects remains poorly understood. Distant-acting transcriptional enhancers control the fine-tuned spatiotemporal expression of genes during critical stages of craniofacial development ...
Sudha Sunil Rajderkar +30 more
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Postnatal Craniofacial Skeletal Development of Female C57BL/6NCrl Mice [PDF]
Frontiers in Physiology, 2017 The craniofacial skeleton is a complex and unique structure. The perturbation of its development can lead to craniofacial dysmorphology and associated morbidities.
Xiaoxi Wei, Nan E Hatch, Min Hu
exaly +4 more sources
High-Resolution Epigenomic Atlas of Human Embryonic Craniofacial Development
Cell Reports, 2018 Summary: Defects in patterning during human embryonic development frequently result in craniofacial abnormalities. The gene regulatory programs that build the craniofacial complex are likely controlled by information located between genes and within ...
Andrea Wilderman +2 more
exaly +4 more sources
Fine-tuning of Wnt signaling by RNA surveillance factor Smg5 in the mouse craniofacial development [PDF]
iScienceSummary: The specific roles of nonsense-mediated mRNA decay (NMD), a translation-dependent RNA quality control mechanism that degrades mRNAs containing premature termination codons (PTCs), in mammalian craniofacial development have remained unclear. Here,
Shicheng Zhu +12 more
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Integrative analysis of transcriptome dynamics during human craniofacial development identifies candidate disease genes [PDF]
Nature Communications, 2023 Craniofacial disorders arise in early pregnancy and are one of the most common congenital defects. To fully understand how craniofacial disorders arise, it is essential to characterize gene expression during the patterning of the craniofacial region.
Tara N. Yankee +10 more
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Transforming growth factor beta signaling and craniofacial development: modeling human diseases in zebrafish [PDF]
Frontiers in Cell and Developmental BiologyHumans and other jawed vertebrates rely heavily on their craniofacial skeleton for eating, breathing, and communicating. As such, it is vital that the elements of the craniofacial skeleton develop properly during embryogenesis to ensure a high quality of
Sabrina C. Fox, Andrew J. Waskiewicz
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Npp1 prevents external tooth root resorption by regulation of cervical cementum integrity
Scientific Reports, 2022 Tooth roots embedded in the alveolar bone do not typically undergo resorption while the bone continues remodeling in its physiological state.
Hwajung Choi +4 more
doaj +1 more source
Scientific Reports, 2023 Orthodontic tooth movement (OTM) occurs through proteolytic remodelling within the periodontium following the application of external force to the tooth.
Fidaa Wazwaz +4 more
doaj +1 more source
Journal of Dental Sciences, 2022 Background/purpose: Baicalin, a natural bioactive flavonoid extracted from Scutellaria baicalensis Georgi, mediates bone metabolism, and recent studies have revealed that it has cell signaling properties.
Ryo Kunimatsu +13 more
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RAB23 coordinates early osteogenesis by repressing FGF10-pERK1/2 and GLI1
eLife, 2020 Mutations in the gene encoding Ras-associated binding protein 23 (RAB23) cause Carpenter Syndrome, which is characterized by multiple developmental abnormalities including polysyndactyly and defects in skull morphogenesis.
Md Rakibul Hasan +5 more
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