Results 31 to 40 of about 76,690 (303)

A Reciprocal Interaction between β-Catenin and Osterix in Cementogenesis

open access: yesScientific Reports, 2017
Although accumulating evidence indicates that both β-catenin and osterix (Osx) are essential for bone and tooth development, few studies have investigated the interaction of these two key proteins in the context of cementogenesis.
Hwajung Choi   +5 more
doaj   +1 more source

Dchs1–Fat4 regulation of polarized cell behaviours during skeletal morphogenesis

open access: yesNature Communications, 2016
How the shape of the sternum is regulated is unclear. Here, the authors identify the Dchs1-Fat4-planar cell polarity pathway as controlling cell orientation and cell intercalation of mesenchymal cells that form skeletal condensations for the mouse ...
Yaopan Mao   +7 more
doaj   +1 more source

Gene expression profiling in the developing secondary palate in the absence of Tbx1 function

open access: yesBMC Genomics, 2018
Background Microdeletion of chromosome 22q11 is associated with significant developmental anomalies, including disruption of the cardiac outflow tract, thymic/parathyroid aplasia and cleft palate.
Maria Zoupa   +5 more
doaj   +1 more source

Candidate genes for obstructive sleep apnea in non-syndromic children with craniofacial dysmorphisms – a narrative review

open access: yesFrontiers in Pediatrics, 2023
Pediatric obstructive sleep apnea (POSA) is a complex disease with multifactorial etiopathogenesis. The presence of craniofacial dysmorphisms influencing the patency of the upper airway is considered a risk factor for POSA development.
Zuzana Marincak Vrankova   +12 more
doaj   +1 more source

BRCA1 and BRCA2 tumor suppressors in neural crest cells are essential for craniofacial bone development. [PDF]

open access: yesPLoS Genetics, 2018
Craniofacial abnormalities, including facial skeletal defects, comprise approximately one-third of all birth defects in humans. Since most bones in the face derive from cranial neural crest cells (CNCCs), which are multipotent stem cells, craniofacial ...
Kohei Kitami   +4 more
doaj   +1 more source

Living with a craniofacial condition: Development of the Craniofacial Experiences Questionnaire (CFEQ) for adolescents and their parents

open access: yes, 2011
Objective: To develop a new instrument (the Craniofacial Experiences Questionnaire, CFEQ) to measure both stressors and positive aspects of living with a craniofacial condition from adolescent and parent perspectives, and to examine its validity and ...
Rosalyn Shute   +5 more
core   +1 more source

Distinct and redundant roles for zebrafish her genes during mineralization and craniofacial patterning

open access: yesFrontiers in Endocrinology, 2022
The Notch pathway is a cell-cell communication system which is critical for many developmental processes, including craniofacial development. Notch receptor activation induces expression of several well-known canonical targets including those encoded by ...
Amanda Stenzel   +6 more
doaj   +1 more source

A ubiquitin-based effector-to-inhibitor switch coordinates early brain, craniofacial, and skin development

open access: yesNature Communications, 2023
The molecular mechanisms that coordinate patterning of the embryonic ectoderm into spatially distinct lineages to form the nervous system, epidermis, and neural crest-derived craniofacial structures are unclear.
Anthony J. Asmar   +13 more
doaj   +1 more source

A Roadmap for the Human Oral and Craniofacial Cell Atlas.

open access: yes, 2022
Oral and craniofacial tissues are uniquely adapted for continuous and intricate functioning, including breathing, feeding, and communication. To achieve these vital processes, this complex is supported by incredible tissue diversity, variously composed ...
Byrd, KM   +3 more
core   +1 more source

The Role of Calcitonin Gene‐Related Peptide in High‐Altitude Headache: A Prospective Field Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective High‐altitude headache (HAH) is a common neurological condition associated with rapid ascent to high altitude. The pathophysiological mechanisms underlying HAH remain incompletely understood. Calcitonin gene‐related peptide (CGRP), a neuropeptide implicated in migraine pathophysiology, may play a key role in the pathophysiology of ...
Roman Schniepp   +4 more
wiley   +1 more source

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