Results 51 to 60 of about 76,690 (303)
Frontiers in Cell and Developmental Biology, 2021 Craniofacial malformations are among the most common birth defects in humans and they often have significant detrimental functional, aesthetic, and social consequences. To date, more than 700 distinct craniofacial disorders have been described.
Sharien Fitriasari +2 more
doaj +1 more source
A Characterization of Pediatric Craniofacial Injuries from Children’s Toys
, 2023 Introduction:Playing with toys contributes significantly to the cognitive, physical, and social development of children. Certain toys, unfortunately, carry the potential for serious craniofacial injury.
Treger, Dylan +5 more
core +1 more source
β‐Adrenergic Signaling Promotes Anti‐Tumor Immunity in TP53‐mutant Oral Squamous Cell Carcinoma
Advanced Science, EarlyView.β‐adrenergic stimulation enhances anti‐tumor immunity in TP53‐deficient oral squamous cell carcinoma by inducing tumor‐derived secretion of CXCL10, which attracts and activates cytotoxic CD8+ T cells. The findings demonstrate that β‐adrenergic signaling alters tumor–immune interactions via CXCL10‐mediated paracrine activation, revealing a neuro‐immune ...
Frederico O. Gleber‐Netto +20 more
wiley +1 more source
Cross‐Modal Denoising and Integration of Spatial Multi‐Omics Data with CANDIES
Advanced Science, EarlyView.In this paper, we introduce CANDIES, which leverages a conditional diffusion model and contrastive learning to effectively denoise and integrate spatial multi‐omics data. We conduct extensive evaluations on diverse synthetic and real datasets, CANDIES shows superior performance on various downstream tasks, including denoising, spatial domain ...
Ye Liu +5 more
wiley +1 more source
Boc modifies the spectrum of holoprosencephaly in the absence of Gas1 function
Biology Open, 2014 Holoprosencephaly is a heterogeneous developmental malformation of the central nervous system characterized by impaired forebrain cleavage, midline facial anomalies and wide phenotypic variation.
Maisa Seppala +3 more
doaj +1 more source
Early stages of retinal development depend on Sec13 function [PDF]
, 2013 ER-to-Golgi transport of proteins destined for the extracellular space or intracellular compartments depends on the COPII vesicle coat and is constitutive in all translationally active cells.
Feng, Yi +7 more
core +1 more source
BMP signalling in craniofacial development
The International Journal of Developmental Biology, 2006 The BMP signalling pathway is conserved throughout evolution and essential for mammalian embryonic and postnatal development and growth. In the vertebrate head, this signal is involved in the development of a variety of structures and shows divergent roles.
Xuguang, Nie +2 more
openaire +3 more sources
Boosting Sensory Nerve‐to‐Bone Interactions Enhances Hedgehog Mediated Calvarial Bone Repair
Advanced Science, EarlyView.Boosting sensory nerve activity via TrkA agonism strongly accelerates calvarial bone repair in adult mice. Furthermore, single‐cell RNA sequencing and neuron–bone interactome analyses identify these sensory neurons as a direct neural source of Hedgehog pathway ligands. Consequently, these ligands drive osteoblast differentiation of skeletal progenitors,
Zhao Li +9 more
wiley +1 more source
Dispersal of Homo sapiens around the Indian Ocean rim: a geometric morphometric study of craniofacial diversity. [PDF]
, 2007 This thesis explores craniofacial diversity found in Homo sapiens around the Indian Ocean rim. Three dimensional landmark data, taken directly from the craniofacial skeleton, are examined in relation to the hypothesised southern dispersal route taken by ...
Buck, Trudi Jane
core
Hand abnormalities associated with craniofacial syndromes
, 2003 One in approximately every 626 newborns has a congenital anomaly of the upper limb. Frequently, patients with craniofacial syndromes may have associated hand anomalies.
Armstrong, Milton B, Panthaki, Zubin J
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