Lessons from joint development for cartilage repair in the clinic
Developmental Dynamics, Volume 250, Issue 3, Page 360-376, March 2021., 2021 Abstract More than 250 years ago, William Hunter stated that when cartilage is destroyed it never recovers. In the last 20 years, the understanding of the mechanisms that lead to joint formation and the knowledge that some of these mechanisms are reactivated in the homeostatic responses of cartilage to injury has offered an unprecedented therapeutic ...
Anne‐Sophie Thorup +2 more
wiley +1 more source
Crouzon’s syndrome with adenotonsillitis: conventional surgery in altered anatomy. [PDF]
, 2013 Background/Objectives: Crouzon’s syndrome is characterized by premature closure of the cranial sutures, midface hypoplasia, orbital deformities & other associated abnormalities.Children with Crouzon syndrome frequently have obstructive sleep apnea ...
Appaji, Mohan +6 more
core +2 more sources
2b or Not 2b: How Opposing FGF Receptor Splice Variants Are Blocking Progress in Precision Oncology
Journal of Oncology, Volume 2021, Issue 1, 2021., 2021 More than ten thousand peer‐reviewed studies have assessed the role of fibroblast growth factors (FGFs) and their receptors (FGFRs) in cancer, but few patients have yet benefited from drugs targeting this molecular family. Strategizing how best to use FGFR‐targeted drugs is complicated by multiple variables, including RNA splicing events that alter the
Richard J. Epstein +3 more
wiley +1 more source
Archives of Plastic Surgery, 2018 Background Non-syndromic craniosynostosis causes craniofacial asymmetry and may persist after cranioplasty. These postoperative asymmetries are primarily depressions.
Yanko Castro-Govea +2 more
doaj +1 more source
The earliest evidence of true lambdoid craniosynostosis: the case of “Benjamina”, a Homo heidelbergensis child [PDF]
, 2010 Background The authors report the morphological and neuroimaging findings of an immature human fossil (Cranium 14) diagnosed with left lambdoid synostosis. Discussion The skull was recovered at the Sima de los Huesos site in Atapuerca (Burgos, Spain).
Arsuaga, Juan Luis +5 more
core +2 more sources
General and oral aspects in Apert syndrome: report of a case [PDF]
, 2015 Background: The present paper describes the general and oral manifestations in a 32-year-old man previously diagnosed with Apert syndrome. Clinical examination revealed features of acrocephalosyndactyly.
Chimenos Küstner, Eduardo +5 more
core +1 more source
The Dura Split Technique in the Treatment of Craniosynostosis : Is It Still an Option? [PDF]
, 2022 Background: The aim of this study was to report the outcome and the complications for patients operated on for craniosynostosis using the dura split technique.
Blair, Richard +2 more
core +1 more source
International Journal of Medical Students, 2013 Fibroblast growth factor receptor (FGFR) gain-of-function mutations form the pathogenic basis of multiple congenital pathologies. A pioneering body of work over the past two decades has established that a unique mutation selection process within the ...
Stuart J. Mires
doaj +1 more source
Phenotypic Expression of Two Candidate Genes of Nonsyndromic Craniosynostosis in Danio rerio [PDF]
, 2020 Phenotypic Expression of Two Candidate Genes of Nonsyndromic Craniosynostosis in Danio rerio Annemarie Carver, Dept. of Biology with Dr. Rita Shiang, Dept.
Carver, Annemarie
core +1 more source
Cranial neural crest cell contribution to craniofacial formation, pathology, and future directions in tissue engineering [PDF]
, 2014 Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/108634/1/bdrc21075 ...
Achilleos +51 more
core +1 more source