Results 21 to 30 of about 18,979 (223)

P38α MAPK-induced senescence in cranial suture progenitor cells promotes craniosynostosis. [PDF]

Commun Biol
Craniosynostosis is a congenital cranial developmental disorder that frequently leads to craniofacial deformities and even neurological dysfunction. The abnormalities in cranial suture progenitor cells (SPC) are considered a key event in craniosynostosis;
Chen Z, Chen Z, Chen X, Yue Y, Wang Y, Hou X, Guo X, Lai C, Song G, Jin X.   +9 more
europepmc   +2 more sources

Association between craniosynostosis and neurodevelopmental disorders: a nationwide claims database. [PDF]

BMC Pediatr
Introduction Autism spectrum disorder (ASD) and attention-deficit/hyperactivity disorder (ADHD) in children and have been increasing in recent years, the identification of risk factors and early intervention are important. Cranial deformities may be risk
Yanai T, Yoshida S, Kawakami K.
europepmc   +2 more sources

Difference in anterior fontanelle closure between non-syndromic craniosynostosis and normal controls: a retrospective cross-sectional study. [PDF]

Ital J Pediatr
Background This study aimed to investigate the differences in anterior fontanelle closure time and size between children with non-syndromic craniosynostosis and controls on CT imaging. Methods A retrospective cross-sectional study was conducted involving
Fu J, Zhan Q, Liu J, Zhao R, Jiang W.
europepmc   +2 more sources

MSC Membrane-Coated circPROSC-siRNA Nanoparticles for Ameliorating Craniosynostosis by Inhibiting Premature Suture Ossification. [PDF]

Adv Sci (Weinh)
Craniosynostosis is a congenital craniofacial disorder caused by excessive osteogenic differentiation of mesenchymal stem cells (MSCs) within cranial sutures.
Weng Z, Chen X, Xu J, Yan Q, Jiao J, Liu Q, Gu A.   +6 more
europepmc   +2 more sources

Apert Syndrome: A Case Report [PDF]

Iranian Journal of Neonatology, 2022
Background: Primary craniosynostosis is a form of premature fusion of the cranial sutures, which commonly occurs prenatally. The condition appears in both syndromic and nonsyndromic forms.Case report: The cause of most cases of primary craniosynostosis ...
Shahin Mafinejad, Hojat Ehteshammanesh, Ghasem Bayani, Hosein Mahmoodzade   +3 more
doaj   +1 more source

The Use of 3D Printed Models for Surgical Simulation of Cranioplasty in Craniosynostosis as Training and Education

Brain Science, 2023
Background: The advance in imaging techniques is useful for 3D models and printing leading to a real revolution in many surgical specialties, in particular, neurosurgery.
J. Uhl, Albert Sufianov, Camillo Ruiz, Yuri Iakimov, Huerta Jose Mogorron, M. E. Encarnación Ramírez, G. Prat, B. Lorea, Matías Baldoncini, E. Goncharov, I. Ramirez, José Rafael Cerda Céspedes, R. Nurmukhametov, N. Montemurro   +13 more
semanticscholar   +1 more source

Syndromic Craniosynostosis: A Comprehensive Review

Cureus, 2023
Craniosynostosis is a fetal skull condition that occurs when one or multiple sutures merge prematurely. This leads to limited growth perpendicular to the fused suture, which results in compensatory growth of cranial bones parallel to it.
Kyriaki Katouni, Aggelos Nikolaou, Theodoros Mariolis, V. Protogerou, Dimosthenis T. Chrysikos, Sophia Theofilopoulou, Dimitrios Filippou   +6 more
semanticscholar   +1 more source

Cranial suture regeneration mitigates skull and neurocognitive defects in craniosynostosis

Cell, 2021
Summary Craniosynostosis results from premature fusion of the cranial suture(s), which contain mesenchymal stem cells (MSCs) that are crucial for calvarial expansion in coordination with brain growth.
Mengfei Yu, Li Ma, Yuan Yuan, Xin Ye, Axel Montagne, Jinzhi He, T. Ho, Yingxi Wu, Zhen Zhao, Naomi S Sta Maria, R. Jacobs, M. Urata, Huiming Wang, B. Zlokovic, Jian-Fu Chen, Y. Chai   +15 more
semanticscholar   +1 more source

Molecular Mechanisms Involved in Craniosynostosis

In Vivo, 2023
Craniosynostosis refers to the early fusion of one or many cranial sutures, causing craniofacial abnormalities observed in 1:2,500 births worldwide. In most cases (85%), craniosynostosis is presented as sporadic anomaly (non-syndromic craniosynostosis ...
C. Yapijakis, Nikolaos Pachis, T. Sotiriadou, Christina Vaila, Vasiliki Michopoulou, S. Vassiliou   +5 more
semanticscholar   +1 more source

Ocular biometric features of pediatric patients with fibroblast growth factor receptor-related syndromic craniosynostosis

Scientific Reports, 2021
Ametropia is reported as a common ophthalmic manifestation in craniosynostosis. We retrospectively compared childhood refractive error and ocular biometric features of fibroblast growth factor receptor (FGFR)-related syndromic craniosynostosis patients ...
Byung Joo Lee, Kihwang Lee, Seung Ah Chung, Hyun Taek Lim   +3 more
doaj   +1 more source