Results 111 to 120 of about 635,017 (399)

3‐[3‐(Phenalkylamino)cyclohexyl]phenols: Synthesis, biological activity, and in silico investigation of a naltrexone‐derived novel class of MOR‐antagonists

open access: yesArchiv der Pharmazie, Volume 356, Issue 1, January 2023., 2023
Based on a simplified version of the morphinan scaffold, 3‐[3‐(phenalkylamino)cyclohexyl]phenol analogues were designed, synthesized and evaluated for their µ‐opioid receptor (MOR) antagonist activity in vitro and in silico. Docking studies indicate a peculiar combination of C‐1 stereochemistry and N‐substitutions as feasibly essential for MOR‐ligand ...
Graziella Tocco   +8 more
wiley   +1 more source

Using Artificial Neural Network to Destroy the Process of Traffic Accident Victims in Yazd Province

open access: yesHealth in Emergencies & Disasters Quarterly, 2021
Background: Road accidents are among the most important causes of death and severe personal and financial injuries. Also, its profound social, cultural, and economic effects threaten human societies.
Mohammad Reza Omidi   +2 more
doaj  

Research of acquisition and prediction method in early weak information of locomotive traction system

open access: yesThe Journal of Engineering, 2019
Many key parts of mechanical equipment gradually enter failure period with service, and failures happen in some of them, it will lead to serious consequences with economic loss and crash of machine and death of human if weak failures cannot be identified
Bin Ren   +4 more
doaj   +1 more source

The Reactions of the Minority Towards Racism in Crash [PDF]

open access: yes, 2013
Crash shows the life of a community in a multicultural city of Los Angeles in a variety of separate scenes. At the end of the story will be seen a common thread that connects each of the characters and events that they experience with other characters ...
Mibianto, S. T. (Shandy)   +1 more
core  

CPR Crash Course [PDF]

open access: yes, 2020
Poetry by Aylin ...
Malcolm, Aylin
core   +1 more source

Locating Crashing Faults based on Crash Stack Traces [PDF]

open access: yesarXiv, 2014
Software crashes due to its increasing complexity. Once a crash happens, a crash report could be sent to software developers for investigation upon user permission. Because of the large number of crash reports and limited information, debugging for crashes is often a tedious and labor-intensive task.
arxiv  

Stock Price Crash Risk: Review of the Empirical Literature

open access: yes, 2017
We survey the burgeoning literature on the determinants and consequences of firm‐specific future stock price crash risk. We synthesise a vast body of literature on the determinants of crash risk, identify weaknesses, and offer future research ...
Ahsan Habib, M. Hasan, Haiyan Jiang
semanticscholar   +1 more source

TCMD: A High‐Throughput and Rapid Method for Screening Antimicrobial Ingredients from Renewable Bio‐Based Resources

open access: yesAdvanced Science, EarlyView.
This study develops a strategy to screen the active compounds from bio‐mixtures via combining transcriptomic profiling and molecular docking. The proposed method demonstrates 100% correction in three different biobased mixtures and is 3–20 times faster than traditional approaches.
Yongdong Xu   +8 more
wiley   +1 more source

SAR exploration of the non‐imidazole histamine H3 receptor ligand ZEL‐H16 reveals potent inverse agonism

open access: yesArchiv der Pharmazie, Volume 356, Issue 1, January 2023., 2023
ZEL‐H16 (1) has been disclosed to be a high‐affinity non‐imidazole H3R (partial) agonist. However, it was found that 1 acts as an inverse agonist for Gαi in various assays. Concise structure–activity relationship studies, molecular pharmacology, and docking were used to shed more light on the properties of 1.
Gábor Wágner   +12 more
wiley   +1 more source

KabOOM: Unsupervised Crash Categorization through Timeseries Fingerprinting [PDF]

open access: yesarXiv, 2021
Modern mobile applications include instrumentation that sample internal application metrics at regular intervals. Following a crash, sample metrics are collected and can potentially be valuable for root-causing difficult to diagnose crashes. However, the fine-grained nature and overwhelming wealth of available application metrics, coupled with frequent
arxiv  

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