Results 91 to 100 of about 102,117 (311)

Targeting Lipopolysaccharide Transport Induces Membrane Lipid Remodeling and Sensitizes Acinetobacter baumannii to Colistin Treatment

Advanced Science, EarlyView.
This study identifies C4 as a lead inhibitor of the Lpt system. Notably, C4 potentiates colistin activity by disrupting LPS transport and remodeling phospholipid homeostasis, revealing a functional interplay between the Lpt and Mla systems. These findings establish a mechanistic link between Lpt inhibition and membrane lipid remodeling, positioning Lpt–
Jianya Luo, Hetianzi Zhang, Jinju Cai, Shuang Zhou, Haijie Zhang, Zhiqiang Wang, Yuan Liu   +6 more
wiley   +1 more source

Substrate‐Controlled Enantiodivergence in Ni‐Catalyzed Access to Phosphorylated Oxindoles With Quaternary Stereocenters

Angewandte Chemie, EarlyView.
An efficient, enantiodivergent synthesis of phosphorylated oxindoles with quaternary stereocenters is achieved via a nickel‐catalyzed intermolecular Heck‐phosphorylation cascade. Employing a single chiral catalyst, either product enantiomer is selectively accessed simply by changing the alkene leaving group. DFT calculations trace this stereodivergence
Haimeng Zhu, Lewen Wang, Shihui Luo, Xinglong Zhang, Jun (Joelle) Wang   +4 more
wiley   +2 more sources

Prevalence of distracted pedestrians while crossing: a study of Malaysia’s situation

MATEC Web of Conferences, 2017
Pedestrian’s crashes account for approximately 7% of road death in Malaysia. Even though the percentage is smaller compared to motorcycle-related crashes, amount of road crashes involving pedestrians in Malaysia is a serious concern.
Mohd Syazwan S., Baba Md. Deros, Nur Zarifah H., Aqbal Hafeez A., Noor Faradila P.   +4 more
doaj   +1 more source

Evaluation of 2005 Arizona crash data reported to the Motor Carrier Management Information System crash file

, 2007
This report is part of a series evaluating the data reported to the Motor Carrier Management Information System (MCMIS) Crash File undertaken by the Center for National Truck and Bus Statistics at the University of Michigan Transportation Research ...
Green, Paul E., Matteson, A.M.
core  

Topological Properties of International Commodity Market: How Uncertainty Affects the Linkages?

Agribusiness, EarlyView.
ABSTRACT The study aims to explore the network topology of the international commodity market by examining the interconnections among 21 commodity futures across various categories, including energy, precious and industrial metals, and agriculture. We analyze the market structure of these commodity futures under both low and high uncertainty conditions
Ibrahim Yagli, Bayram Deviren
wiley   +1 more source

Mitochondria‐Damaging Self‐Reporting Probe for Cancer Therapy

Angewandte Chemie, EarlyView.
We developed a class of self‐reporting cationic chemotherapeutic probes that selectively induce mitochondrial damage and apoptosis in cancer cells. Their unique mitochondria‐to‐nucleus fluorescence migration enables real‐time visualization of the therapeutic process. ABSTRACT Mitochondrial damage induced by chemotherapeutic agents through disruption of
Hai Xu, Yura Lee, Sanghee Yoon, Yun Wang, Yejin Cho, Seongyu Choi, Lu Lu, Hua Zhang, Sun Choi, Ki Taek Nam, Juyoung Yoon   +10 more
wiley   +2 more sources

Heart rate variability (HRV) and muscular system activity (EMG) in cases of crash threat during simulated driving of a passenger car

International Journal of Occupational Medicine and Environmental Health, 2013
Objectives: The aim of the study was to verify whether simultaneous responses from the muscular and circulatory system occur in the driver's body under simulated conditions of a crash threat.
Krystyna Zużewicz, Danuta Roman-Liu, Maria Konarska, Paweł Bartuzi, Krzysztof Matusiak, Dariusz Korczak, Zbigniew Lozia, Marek Guzek   +7 more
doaj   +1 more source

Evaluation of 2008 North Dakota crash data reported to the Motor Carrier Management Information System Crash File [PDF]

, 2009
This report is part of a series evaluating the data reported to the Motor Carrier Management Information System (MCMIS) Crash File undertaken by the Center for National Truck and Bus Statistics at the University of Michigan Transportation Research ...
Matteson, Anne, Blower, Daniel Frederick
core  

Large Language Model in Materials Science: Roles, Challenges, and Strategic Outlook

Advanced Intelligent Discovery, EarlyView.
Large language models (LLMs) are reshaping materials science. Acting as Oracle, Surrogate, Quant, and Arbiter, they now extract knowledge, predict properties, gauge risk, and steer decisions within a traceable loop. Overcoming data heterogeneity, hallucinations, and poor interpretability demands domain‐adapted models, cross‐modal data standards, and ...
Jinglan Zhang, Xinyi Chen, Xu Ye, Yulin Yang, Bin Ai   +4 more
wiley   +1 more source

Evaluation of Michigan crash data reported to Motor Carrier Management Information System Crash File

, 2004
Includes bibliographical references (p. 23)Special reportThis is one of a series of papers presenting the results of an evaluation of the Motor Carrier Management Information System (MCMIS) Crash File undertaken by the Center for National Truck and Bus ...
Blower, Daniel Frederick, Matteson, A.
core