Results 81 to 90 of about 102,117 (311)

Evaluation of 2008 Kansas crash data reported to the Motor Carrier Management Information System Crash File

open access: yes, 2010
This report is part of a series evaluating the data reported to the Motor Carrier Management Information System (MCMIS) Crash File undertaken by the Center for National Truck and Bus Statistics at the University of Michigan Transportation Research ...
Matteson, Anne, Blower, Daniel Frederick
core  

AI‐Physics‐Experiment Trinity for Integrated Protein Dynamics Modeling

open access: yesAdvanced Science, EarlyView.
This review unites experiments, physics‐based simulations, and AI as a synergistic triad for protein dynamics modeling. It highlights integrative strategies, resolves sampling and forcefield bottlenecks, and outlines challenges and future directions for accurate, interpretable conformational ensemble prediction.
Chen Shi   +4 more
wiley   +1 more source

Surfaceome Reprogramming of Stemsomes Promotes Lung Cancer Targeting via Potentiated Receptor–Ligand Interactions

open access: yesAdvanced Science, EarlyView.
This study presents a surfaceome‐reprogramming strategy for mutation‐independent lung cancer therapy by repurposing dexamethasone to prime mesenchymal stem cell‐derived nanovesicles. The engineered vesicles leverage multi‐valent interactions mediated by upregulated adhesion proteins, EPHA2, and NOTCH3.
Geunhye Kim   +8 more
wiley   +1 more source

A Systematic Review of GIS-Driven Road Traffic Accident Evaluation

open access: yesVehicles
The review has explored the application of Geographic Information Systems (GIS) in evaluating road traffic crashes, stressing its role in identifying crash spatial patterns and hotspots. GIS offers a framework for integrating spatial and non-spatial data,
Basha Fayissa Deressa   +4 more
doaj   +1 more source

Evaluation of 2006 Maine crash data reported to Motor Carrier Management Information System crash file

open access: yes, 2008
Special reportThis report is part of a series evaluating the data reported to the Motor Carrier Management Information System (MCMIS) Crash File undertaken by the Center for National Truck and Bus Statistics at the University of Michigan Transportation ...
Matteson, Anne, Blower, D.
core  

Tandem Duplication‐Driven Neofunctionalization of UDP‐Glycosyltransferases Shapes the Diversification of Triterpenoid Saponins in the Cucurbitaceae

open access: yesAdvanced Science, EarlyView.
We present a chromosome‐level genome assembly of Siraitia grosvenorii and, through comparative genomics, uncover a conserved UGT73 tandem array driving triterpenoid saponin diversification in Cucurbitaceae. Crystalized SgUGT73AM30 further reveals the regioselectivity mechanism underlying its catalytic activity.
Guangyi Wang   +13 more
wiley   +1 more source

Catalytic Functionalization of Unactivated π‐Bonds Enabled by Bidentate Directing Auxiliaries

open access: yesAngewandte Chemie, EarlyView.
This review explores how bidentate directing auxiliaries have advanced transition‐metal catalysis for unactivated alkene/alkyne functionalization. By leveraging chelated intermediates, bidentate directing auxiliaries enable precise hydrofunctionalization, difunctionalization, and C─H activation of π‐bonds with unique selectivity and reactivity.
Seunghyeon Cho   +4 more
wiley   +2 more sources

Risk Factor Profile of Motorcycle Crash Victims in Rural Kenya

open access: yesThe Annals of African Surgery, 2015
Background: Road traffic injuries involvingmotorcycles are increasing especially in rural Kenya resulting in both human and economic loss. This study was done to identify the risk factors and the host characteristics associated with motorcycle injury ...
Karau PB   +4 more
doaj  

Mapping Bicycle Crash Risk Patterns on the Local Scale

open access: yesSafety, 2016
Currently, mainly aggregated statistics are used for bicycle crash risk calculations. Thus, the understanding of spatial patterns at local scale levels remains vague.
Martin Loidl   +3 more
doaj   +1 more source

Evaluation of Maryland crash data reported to Motor Carrier Management Information System Crash File

open access: yes, 2006
This document is part of a series of reports evaluating the data reported to the Motor Carrier Management Information System (MCMIS) Crash file undertaken by the Center for National Truck and Bus Statistics at the University of Michigan Transportation ...
Green, Paul E., Matteson, A.
core  

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