Results 111 to 120 of about 361,160 (313)
CRC-like organoids with the acquired mutations related to the stage.
, 2019 CRC-like organoids with the acquired mutations related to the stage.
Silvia Cruz-Gil (7037249) +6 more
core +1 more source
Leveraging Artificial Intelligence and Large Language Models for Cancer Immunotherapy
Advanced Science, EarlyView.Cancer immunotherapy faces challenges in predicting treatment responses and understanding resistance mechanisms. Artificial intelligence (AI) and machine learning (ML) offer powerful solutions for cancer immunotherapy in patient stratification, biomarker discovery, treatment strategy optimization, and foundation model development.
Xinchao Wu +4 more
wiley +1 more source
, 2005 In the previous research CRC CI 2001-010-C “Investment Decision Framework for\ud Infrastructure Asset Management”, a method for assessing variation in cost estimates\ud for road maintenance and rehabilitation was developed.
core
The Importance of Metal‐Organic Framework Linker Atoms for CO2 Reduction: A DFT Study
Advanced Science, EarlyView.Using DFT, we examine the role of linker atoms in CO2 reduction on copper‐based metal organic frameworks (Cu MOFs). Our calculations reveal that linker atoms may serve as both CO2 and H‐shuttling sites and suggest linker electrostatics as a descriptor for linker activity. ABSTRACT Although the metal within the secondary building unit of a metal‐organic
Ugochukwu Nwosu, Samira Siahrostami
wiley +1 more source
The Dual Role of NRF2 in Colorectal Cancer: Targeting NRF2 as a Potential Therapeutic Approach
Journal of Inflammation ResearchMengyun Hu,1 Lingling Yuan,1 Jie Zhu2 1School of Clinical Medicine, Chengdu University of Traditional Chinese Medicine, Chengdu, People’s Republic of China; 2Hospital of Chengdu University of Traditional Chinese Medicine, Oncology Department II, Chengdu,
Hu M, Yuan L, Zhu J
doaj
Advanced Science, EarlyView.In colorectal cancer, high expression of the DNA repair protein EEPD1 correlates with immune exclusion and poor prognosis. This study demonstrates that EEPD1 depletion induces genomic instability, leading to cytosolic DNA accumulation and subsequent activation of the cGAS‐STING‐type I interferon pathway. This cascade remodels the tumor microenvironment
Liyun Huo +8 more
wiley +1 more source
International Journal of General MedicineFeng Zhang,1,2,* Kai-Li Zhu,3,* Rui Chen,1,* Fei Su1,4 1Department of Oncology, The First Hospital of Lanzhou University, Lanzhou, Gansu Province, 73000, People’s Republic of China; 2Department of Oncology, The First Hospital of Lanzhou ...
Zhang F, Zhu KL, Chen R, Su F
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Report : stochastic analysis of road asset data for maintenance cost prediction
, 2005 Reliable budget/cost estimates for road maintenance and rehabilitation are subjected\ud to uncertainties and variability in road asset condition and characteristics of road\ud users. The CRC CI research project 2003-029-C ‘Maintenance Cost Prediction for\
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Advanced Science, EarlyView.A multifunctional nanoagonist (cDZ@IP) enables nano‐metabolite–driven multimodal activation of the STING pathway and enhanced immune recognition, achieving potent antitumor immunity and suppressing tumor growth and metastasis. This strategy highlights the rational design of therapeutic metabolites and establishes a new paradigm bridging nanomedicine ...
Kepeng Hu +17 more
wiley +1 more source